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06:02
Arbovirus Infections As Screening Tools for the Identification of Viral Immunomodulators and Host Antiviral Factors
Published on: September 13, 2018
7.4K
Travelling arboviruses: A historical perspective
1Uniformed Services University of the Health Sciences, 5824 Edson Lane, N. Bethesda, 20852, Maryland, USA.
Travel Medicine and Infectious Disease
|September 1, 2019
Summary
Chikungunya, dengue, yellow fever, and Zika viruses are zoonoses transmitted by Aedes aegypti mosquitoes. This review explores factors influencing their invasiveness and pathogenicity, crucial for understanding disease spread.
Area of Science:
- Arbovirology
- Epidemiology
- Pathogen evolution
Background:
- Chikungunya, dengue, yellow fever, and Zika viruses are zoonotic arboviruses.
- These viruses are transmitted by the Aedes aegypti mosquito.
- They have a history of global travel and emergence.
Observation:
- Understanding the epidemiology of these viruses requires examining past behaviors.
- Unexplained restraints on viral travel are critical to investigate.
- Mechanisms contributing to invasiveness and pathogenicity need review.
Findings:
- These viruses exhibit complex zoonotic transmission cycles involving non-human primates.
- Successful adaptation to Aedes aegypti facilitates urban transmission.
- Historical data reveals repeated global dissemination of these pathogens.
Implications:
- Identifying mechanisms of invasiveness and pathogenicity is key for public health.
- Understanding viral travel patterns aids in predicting and controlling outbreaks.
- This review synthesizes knowledge on factors driving arboviral disease emergence.
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