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Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks11:18

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An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
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Related Experiment Video

Updated: Jan 20, 2026

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks
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NPA: an R package for computing network perturbation amplitudes using gene expression data and two-layer networks.

Florian Martin1, Sylvain Gubian2, Marja Talikka2

  • 1PMI R&D, Philip Morris Products S.A, Quai Jeanrenaud 5, CH-2000, Neuchâtel, Switzerland. Florian.Martin@pmi.com.

BMC Bioinformatics
|September 5, 2019
PubMed
Summary

The NPA package analyzes gene expression data using two-layer networks to assess biological mechanisms and potential toxicity. It computes a Biological Impact Factor to quantify overall perturbation, aiding systems toxicology research.

Failed At:

2026-06-19T13:38:19.667917+00:00

Keywords:
Gene expressionNetwork modelsSystems toxicology

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