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Updated: Jan 20, 2026

Correlative Light- and Electron Microscopy Using Quantum Dot Nanoparticles
Published on: August 7, 2016
[Variants of bone tissue modification in chronic otitis media according to light and electron microscopy]
I D Dubinets1, M Yu Korkmazov1, A I Sinitsky1
1Federal State Budgetary Educational Institution of Higher Education 'South Urals State Medical University' of the Ministry of Healthcare of the Russian Federation, Chelyabinsk, Russia, 454092.
Purpose:
Analysis of the results of surgical treatment of patients with chronic hepatitis C, depending on the characteristics of structural changes in the bone tissue of the middle ear.
Patients And Methods:
Bone tissue of the retrotympanal cavities was obtained when performing various types of reconstructive sanitizing interventions: 123 samples for light microscopy and 35 samples in parallel for electron microscopy.
Results:
The article presents the results of a retrospective analysis of the clinical features and surgical treatment of 177 patients with chronic suppurative otitis media. For histomorphological assessment, pathological processes of structural changes in the bone tissue of the middle ear were studied using acid-free microwave decalcification.
Conclusion:
The obtained data allowed to establish options for ultrastructural changes in the bone tissue of varying severity in chronic inflammation depending on the types of structure of the mastoid during the duration of the disease for more than 10 years.
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