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Updated: Jan 20, 2026

Preparation of Silver-Palladium Alloyed Nanoparticles for Plasmonic Catalysis under Visible-Light Illumination
Published on: August 18, 2020
Asymmetric Retro-Claisen Reaction by Synergistic Chiral Primary Amine/Palladium Catalysis
Yanfang Han1,2, Long Zhang3, Sanzhong Luo3
1Key Laboratory of Molecular Recognition and Function , Institute of Chemistry, Chinese Academy of Sciences , Beijing 100190 , China.
Abstract:
We described herein a chiral primary amine/palladium catalyzed asymmetric retro-Claisen reaction of β-diketones with salicylic carbonates. A series of chiral α-alkylated ketones and macrolides were obtained with good yields and excellent enantioselectivities upon a sequence of decarboxylative benzylation, retro-Claisen cleavage, and enamine protonation. This strategy features broad substrate scope, mild conditions, as well as high atom economy with salicylic carbonates as the o-quinone methide precursors.
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