Related Experiment Video
Updated: Jan 20, 2026
14:45
Enumeration of Major Peripheral Blood Leukocyte Populations for Multicenter Clinical Trials Using a Whole Blood Phenotyping Assay
Published on: September 16, 2012
15.5K
Ponticulus posticus: clinical and CBCT analysis in a young Italian population.
D Tripodi1, M Tieri1, P Demartis1
1Department of Medical, Oral and Biotechnological Sciences, University "G. d'Annunzio" Chieti - Pescara, Chieti, Italy.
European Journal of Paediatric Dentistry
|September 7, 2019
Summary
Ponticulus Posticus (PP), a common anomaly in young Italians, affects 28.24% of patients and is linked to symptoms like headaches. Early detection via CBCT is crucial for managing cranio-cervicofacial pain.
Area of Science:
- Anatomy
- Radiology
- Pediatric Dentistry
Background:
- Ponticulus Posticus (PP) is an anatomical variation of the atlas vertebra.
- Its prevalence and clinical significance in pediatric populations require further investigation.
Purpose of the Study:
- To determine the prevalence and morphological characteristics of Ponticulus Posticus (PP) in young Italian patients.
- To assess the association between PP and related symptoms such as headache, tinnitus, and migraine.
- To evaluate PP prevalence across different age and gender groups.
Main Methods:
- Retrospective analysis of cone-beam computed tomography (CBCT) scans from Italian patients of developmental age (mean age 12.61 ± 2.69).
- Evaluation of medical records for symptom correlation.
- Statistical analysis using the chi-squared (?²) test to compare prevalence rates.
Main Results:
- The overall prevalence of PP was 28.24%.
- PP was significantly more prevalent in males (35.27%) than females (21.42%).
- Bilateral PP occurred in 74.33% of cases, monolateral in 25.67%.
- Associated symptoms included headache (32.43%), tinnitus (6.08%), and migraine (3.38%).
- Headache prevalence varied by age group, peaking in the 12-14 year olds (54.17%).
Conclusions:
- Ponticulus Posticus is a relatively common anomaly in young Italian individuals.
- PP should be identified in lateral cephalograms and CBCT scans, regardless of symptoms or age, for comprehensive diagnosis.
- Recognition of PP is important for the differential diagnosis and management of cranio-cervicofacial pain in developing patients.
Related Concept Videos
07:03Analysis of Earthworm Populations in Soil
17.3K
Source: Laboratories of Margaret Workman and Kimberly Frye - Depaul University
Using mustard, Lumbricus terrestris earthworm populations can be sampled directly from soil depths without landscape disturbance or toxicity. Earthworms can then be counted for data and statistical analysis using a bar graph and student’s t-test.
Monitoring earthworm populations is a vital technique for environmental scientists, as multiple species of earthworms (most notably those from the suborder Lumbricina)...
Using mustard, Lumbricus terrestris earthworm populations can be sampled directly from soil depths without landscape disturbance or toxicity. Earthworms can then be counted for data and statistical analysis using a bar graph and student’s t-test.
Monitoring earthworm populations is a vital technique for environmental scientists, as multiple species of earthworms (most notably those from the suborder Lumbricina)...
17.3K
14:45Enumeration of Major Peripheral Blood Leukocyte Populations for Multicenter Clinical Trials Using a Whole Blood Phenotyping Assay
15.5K
In this report, we demonstrate the staining and analysis steps of a phenotyping assay performed on fresh whole blood to enumerate major innate and adaptive leukocyte populations. We emphasize considerations for performing these procedures in the context of a multicenter clinical...
15.5K
01:12Analysis of Population Pharmacokinetic Data
684
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
684
06:26Analysis of Side Population in Solid Tumor Cell Lines
4.8K
A convenient, fast, and cost-effective method to measure the proportion of side population cells in solid tumor cell lines is...
4.8K
02:04Conservation of Small Populations
16.6K
Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
16.6K
01:25What is Population Genetics?
64.5K
A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
64.5K