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Updated: Jan 19, 2026

Cutaneous Surgical Denervation: A Method for Testing the Requirement for Nerves in Mouse Models of Skin Disease
Published on: June 26, 2016
[Anterior cutaneous nerve entrapment syndrome]
Kenney Fehrenkamp Pedersen1, Rudi Roumen, Marc Scheltinga
1kenneyfpedersen@gmail.com.
Abstract:
In this review, we summarise the current knowledge of anterior cutaneous nerve entrapment syndrome (ACNES), which is a well-documented but overlooked and relatively common cause of sudden abdominal wall pain. Patients with ACNES often end up with chronic abdominal pain, which leads to reduced quality of life. The diagnosis is based on patient history, pain characteristics, clinical bedside examinations and a diagnostic injection of local anaesthetics. More than 80% of patients can be treated with good effect when employing a step-up strategy. Patients should be referred to a dedicated surgical centre for examination and treatment, when ACNES is suspected.
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