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Related Experiment Video

Updated: Jan 19, 2026

Simple and Rapid Method to Obtain High-quality Tumor DNA from Clinical-pathological Specimens Using Touch Imprint Cytology

Simple and Rapid Method to Obtain High-quality Tumor DNA from Clinical-pathological Specimens Using Touch Imprint Cytology

Published on: March 21, 2018

[Current methods in molecular pathology].

Jürgen Hench¹, Philip M Jermann¹, Ivana Bratic Hench¹

¹Institut für Pathologie, Universitätsspital Basel, Basel.

Therapeutische Umschau. Revue Therapeutique

|September 10, 2019

Summary

This summary is machine-generated.

Molecular pathology uses advanced genetic and epigenetic analysis for tumor diagnosis, prognosis, and treatment. This review covers current methods for detecting critical tumor alterations, enhancing patient care.

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Area of Science:

Oncology
Molecular Pathology
Genetics

Background:

Traditional tumor analysis relied on macroscopic and microscopic examination.
Recent advancements have significantly increased understanding of tumor-specific genetic and epigenetic alterations.
These molecular changes are crucial for accurate diagnosis, prognosis, and therapeutic strategies.

Purpose of the Study:

To review current methodologies employed in molecular pathology.
To highlight the importance of detecting genetic alterations in tumors.
To provide an overview of techniques for analyzing mutations, translocations, and methylation profiles.

Main Methods:

Review of current literature on molecular pathology techniques.
Focus on methods for detecting genetic and epigenetic alterations in tumors.
Discussion of techniques applicable to pathological work-up.

Main Results:

Identification of key molecular alterations impacting tumor diagnosis and prognosis.
Overview of various methods for genetic analysis.
Emphasis on the clinical relevance of molecular pathology.

Conclusions:

Molecular pathology methods are essential for modern tumor analysis.
Accurate detection of genetic alterations guides diagnosis, prognosis, and therapy.
The review provides a comprehensive overview of current molecular pathology techniques.