Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Semi-Quantitative Analysis of Peptidoglycan by Liquid Chromatography Mass Spectrometry and Bioinformatics09:09

Semi-Quantitative Analysis of Peptidoglycan by Liquid Chromatography Mass Spectrometry and Bioinformatics

5.1K
This protocol covers a detailed analysis of peptidoglycan composition using liquid chromatography mass spectrometry coupled with advanced feature extraction and bioinformatic analysis...
5.1K
Quantitative Analysis of the Cellular Lipidome of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry08:56

Quantitative Analysis of the Cellular Lipidome of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry

7.8K
We present a protocol using liquid chromatography coupled with tandem mass spectrometry to identify and quantify major cellular lipids in Saccharomyces cerevisiae. The described method for a quantitative assessment of major lipid classes within a yeast cell is versatile, robust, and...
7.8K
Extraction of Non-Protein Amino Acids from Cyanobacteria for Liquid Chromatography-Tandem Mass Spectrometry Analysis08:14

Extraction of Non-Protein Amino Acids from Cyanobacteria for Liquid Chromatography-Tandem Mass Spectrometry Analysis

4.2K
The present protocol describes the extraction of non-protein amino acids from biological matrices via trichloroacetic acid (TCA) protein precipitation and acid hydrolysis before analysis using liquid chromatography-tandem mass spectrometry.
4.2K
Lipid Droplet Isolation for Quantitative Mass Spectrometry Analysis10:23

Lipid Droplet Isolation for Quantitative Mass Spectrometry Analysis

10.7K
Lipid droplets are important organelles for the replication of several pathogens, including the Hepatitis C Virus (HCV). We describe a method to isolate lipid droplets for quantitative mass spectrometry of associated proteins; it can be used under a variety of conditions, such as virus infection, environmental stress, or drug...
10.7K
Synthesis and Mass Spectrometry Analysis of Oligo-peptoids11:44

Synthesis and Mass Spectrometry Analysis of Oligo-peptoids

11.3K
A protocol is described for the manual synthesis of oligo-peptoids followed by sequence analysis by mass...
11.3K
Quantitative Metabolomics of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry07:25

Quantitative Metabolomics of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry

4.9K
We present a protocol for the identification and quantitation of major classes of water-soluble metabolites in the yeast Saccharomyces cerevisiae. The described method is versatile, robust, and sensitive. It allows the separation of structural isomers and stereoisomeric forms of water-soluble metabolites from each...
4.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Analysis of Melting Phenomena of the Alkali Halides: What Causes the Low Melting Points of the Lithium Halides?

Journal of mass spectrometry : JMS·2026
Same author

A pilot study showcasing the difficulties in endoscopic biliary drainage using uncovered self-expanding metal stents for resectable perihilar cholangiocarcinoma.

Scandinavian journal of gastroenterology·2025
Same author

Precision Localization of Lipid-Based Nanoparticles by Dual-Fluorescent Labeling for Accurate and High-Resolution Imaging in Living Cells.

Small science·2025
Same author

Long-term Double-J stenting is superior to short-term Single-J stenting in kidney transplantation.

PloS one·2025
Same author

Holmium-166 radioembolisation dosimetry in HCC.

European journal of nuclear medicine and molecular imaging·2024
Same author

Hybrid FDG-PET/MRI for Diagnosis and Clinical Management of Patients with Suspected Perihilar Cholangiocarcinoma: A Feasibility Pilot Study.

Nuclear medicine and molecular imaging·2024
Same journal

Mass Spectrometry Insights Into Post-Translational Modifications in Extracellular Vesicles.

Mass spectrometry reviews·2026
Same journal

Standardization Challenges and Breakthroughs in Apolipoprotein B Detection: From Immunoassays to LC-MS/MS.

Mass spectrometry reviews·2026
Same journal

The Rise of Trapped Ion Mobility Spectrometry: Principles, Applications, and Recent Developments.

Mass spectrometry reviews·2026
Same journal

Carlito B. Lebrilla: Building Instruments, Fields and Opportunities From the Ground up.

Mass spectrometry reviews·2026
Same journal

Recent Advances in Top-Down Proteomics for Single-Cell Research.

Mass spectrometry reviews·2026
Same journal

Applications of Top-Down Protein Analysis in Clinical Diagnostics.

Mass spectrometry reviews·2026
See all related articles

Related Experiment Video

Updated: Jan 19, 2026

Semi-Quantitative Analysis of Peptidoglycan by Liquid Chromatography Mass Spectrometry and Bioinformatics
09:09

Semi-Quantitative Analysis of Peptidoglycan by Liquid Chromatography Mass Spectrometry and Bioinformatics

Published on: October 13, 2020

5.1K

Collagen analysis with mass spectrometry.

Nick A van Huizen1,2, Jan N M Ijzermans2, Peter C Burgers1

  • 1Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands.

Mass Spectrometry Reviews
|September 10, 2019
PubMed
Summary
This summary is machine-generated.

Mass spectrometry offers powerful tools for analyzing collagen, including its abundance and modifications. This review highlights its potential for detailed collagen research.

Keywords:
collagenmass spectrometrypost-translational modificationproteomics

More Related Videos

Quantitative Analysis of the Cellular Lipidome of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry
08:56

Quantitative Analysis of the Cellular Lipidome of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry

Published on: March 8, 2020

7.8K
Extraction of Non-Protein Amino Acids from Cyanobacteria for Liquid Chromatography-Tandem Mass Spectrometry Analysis
08:14

Extraction of Non-Protein Amino Acids from Cyanobacteria for Liquid Chromatography-Tandem Mass Spectrometry Analysis

Published on: December 9, 2022

4.2K

Related Experiment Videos

Last Updated: Jan 19, 2026

Semi-Quantitative Analysis of Peptidoglycan by Liquid Chromatography Mass Spectrometry and Bioinformatics
09:09

Semi-Quantitative Analysis of Peptidoglycan by Liquid Chromatography Mass Spectrometry and Bioinformatics

Published on: October 13, 2020

5.1K
Quantitative Analysis of the Cellular Lipidome of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry
08:56

Quantitative Analysis of the Cellular Lipidome of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry

Published on: March 8, 2020

7.8K
Extraction of Non-Protein Amino Acids from Cyanobacteria for Liquid Chromatography-Tandem Mass Spectrometry Analysis
08:14

Extraction of Non-Protein Amino Acids from Cyanobacteria for Liquid Chromatography-Tandem Mass Spectrometry Analysis

Published on: December 9, 2022

4.2K

Area of Science:

  • Biochemistry
  • Proteomics
  • Molecular Biology

Background:

  • Collagen is a crucial structural protein with diverse biological roles.
  • Research interest has shifted towards understanding collagen abundance and modifications.
  • Traditional methods have limitations in detailed collagen analysis.

Purpose of the Study:

  • To review the applications of mass spectrometry in collagen research.
  • To illustrate the potential of mass spectrometry for in-depth collagen analysis.
  • To highlight advancements in studying collagen abundance and modifications.

Main Methods:

  • Mass spectrometry-based techniques are central to the described analyses.
  • Methods cover identification, quantification, and characterization of collagen.
  • Focus on analyzing post-translational modifications and supramolecular organization.

Main Results:

  • Mass spectrometry enables comprehensive investigation of collagen.
  • Techniques allow for precise identification and quantification.
  • Advanced methods reveal insights into collagen modifications and organization.

Conclusions:

  • Mass spectrometry is a versatile and powerful tool for collagen research.
  • It facilitates a deeper understanding of collagen's role in biological systems.
  • The review underscores the growing importance of mass spectrometry in proteomics and molecular biology.