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Quantifying Pain Location and Intensity with Multimodal Pain Body Diagrams09:00

Quantifying Pain Location and Intensity with Multimodal Pain Body Diagrams

Current pain scales used to quantify pain severity, such as visual analog scales, fail to capture the complexity of subjective pain experiences. Pain body diagrams are qualitative but may be more informative. The goal of this method is to extract quantitative metrics from pain body diagrams using novel pressure-hue...
4.4K
Intracranial Pharmacotherapy and Pain Assays in Rodents02:26

Intracranial Pharmacotherapy and Pain Assays in Rodents

Here we present a protocol to perform intracranial pharmacological experiments followed by pain behavior assays in rodents. This protocol allows researchers to deliver molecular and cellular targets in the brain, for pharmacologic agents in the treatment of...
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An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)14:56

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)

Diffuse noxious inhibitory control, temporal summation and wound hyperalgesia testing are demonstrated in the obstetric patient. These tests evaluate inhibitory and excitatory mechanisms of pain processing and are here utilized to evaluate endogenous analgesia at different time-points during pregnancy and the peripartum period to help reveal individual s risk for persistent...
21.9K
A Protocol of Manual Tests to Measure Sensation and Pain in Humans07:28

A Protocol of Manual Tests to Measure Sensation and Pain in Humans

The goal of this procedure is to demonstrate a battery of quantitative techniques for sensory and pain measurement in humans. The equipment and techniques described are commonly found in pain clinics or are easy to...
21.6K
Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain08:03

Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain

We have developed an evoked measure of arthritis pain and coupled it with a standardized method for measuring spontaneous pain in different murine models of chemically induced arthritis. These measures are sensitive and reproducible for different types of joint...
8.9K
Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing09:16

Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing

By assessing pain in response to repetitive or different types of standardized stimuli, dynamic quantitative sensory testing (QST) can reveal changes in the central processing of pain. We present methods to optimize and individualize two dynamic QST measures: temporal summation (TS) and conditioned pain modulation...
17.5K