Related Experiment Video
Updated: Jan 19, 2026
12:24
Sterile Tissue Harvest in Rodents
Published on: April 30, 2023
36.5K
Quality Control: Hand and Glove Sanitizing in Sterile Compounding, Part 1.
Nicole Mh Greeson1, William Mixon2, Kirk Huslage3
1Occupational Hygiene and Safety Division, Duke University and Health System, Durham, North Carolina. nicole.greeson@duke.edu.
International Journal of Pharmaceutical Compounding
|September 13, 2019
Summary
Strict hand hygiene and glove sanitizing protocols are crucial in pharmaceutical compounding to maintain sterile preparation safety and effectiveness. This article focuses on alcohol-based hand rubs, detailing their use, mechanism, and selection for compounding environments.
Area of Science:
- Pharmaceutical Science
- Infection Control
Background:
- Sterile pharmaceutical compounding demands rigorous hand hygiene and glove sanitizing to ensure product safety and efficacy.
- Effective antimicrobial agents like alcohols and chlorhexidine gluconate are essential, with no documented clinical resistance.
- Part 1 of a series, this article focuses on alcohol-based hand rubs for sterile compounding.
Purpose of the Study:
- To define terminology related to hand sanitizers in sterile compounding.
- To examine the necessity, requirements, mechanism of action, and composition of hand sanitizers.
- To provide guidance on selecting and applying alcohol-based hand rubs for compounding.
Main Methods:
- Review of scientific literature on hand hygiene agents and protocols.
- Analysis of the properties and applications of alcohol-based hand rubs.
- Development of a protocol for the use of hand sanitizers in sterile compounding.
Main Results:
- Alcohols are highly effective antimicrobial agents against bacteria, viruses, and fungi.
- Selection of hand sanitizers depends on factors like efficacy, compatibility, and patient safety.
- A protocol for applying alcohol-based hand rubs is presented.
Conclusions:
- Adherence to proper hand hygiene and glove sanitizing protocols is paramount in sterile compounding.
- Alcohol-based hand rubs are suitable and effective agents for maintaining aseptic technique.
- Understanding sanitizer properties and application is key to ensuring sterile preparation integrity.
Related Concept Videos
01:05Quality Control
1.2K
Quality control is one of the three cyclical quality assurance activities that help keep a system under statistical control. Typical quality control activities include creating quality control charts, conducting proficiency testing, and documenting and archiving results.
Quality control helps track data, visualize trends, and identify variations, making it easier to detect deviations that may affect the accuracy of an analysis. One way to do this is by generating a quality control chart, which...
Quality control helps track data, visualize trends, and identify variations, making it easier to detect deviations that may affect the accuracy of an analysis. One way to do this is by generating a quality control chart, which...
1.2K
12:24Sterile Tissue Harvest
36.5K
Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN
In 1959 The 3 R's were introduced by W.M.S. Russell and R.L. Burch in their book The Principles of Humane Experimental Technique. The 3 R's are replacement, reduction, and refinement of the use of animals in research.1 The use of cell lines and tissue cultures that originated from research animals is a replacement technique, as it allows for many experiments to be conducted in vitro....
In 1959 The 3 R's were introduced by W.M.S. Russell and R.L. Burch in their book The Principles of Humane Experimental Technique. The 3 R's are replacement, reduction, and refinement of the use of animals in research.1 The use of cell lines and tissue cultures that originated from research animals is a replacement technique, as it allows for many experiments to be conducted in vitro....
36.5K
09:27DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning
38.6K
We demonstrate the use of DNA microarrays for expression profiling of the nervous system. We describe RNA quality control, sample labeling, and array hybridization and...
38.6K
11:50Purification and Quality Control of Recombinant Septin Complexes for Cell-Free Reconstitution
2.6K
In vitro reconstitution of cytoskeletal proteins is a vital tool to understand the basic functional properties of these proteins. The present paper describes a protocol to purify and assess the quality of recombinant septin complexes, which play a central role in cell division and migration.
2.6K
15:06Compound Administration I
109.8K
Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN
As many research protocols require that a substance be injected into an animal, the route of delivery and the amount of the substance must be accurately determined. There are several routes of administration available in the mouse and rat. Which route to use is determined by several factors of the substance to be injected: the pH of the solution, the volume required for the desired dosage, and...
As many research protocols require that a substance be injected into an animal, the route of delivery and the amount of the substance must be accurately determined. There are several routes of administration available in the mouse and rat. Which route to use is determined by several factors of the substance to be injected: the pH of the solution, the volume required for the desired dosage, and...
109.8K
05:17Preparation of High-Quality Fermented Fish Product
11.0K
The goal of the protocol is to provide an industrialized fish fermentation technique based on inoculation of Saccharomyces...
11.0K