Related Experiment Video

Updated: Jan 19, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.8K

A Case of Sirolimus-Induced Interstitial Lung Disease After Liver Transplantation

Narendra S Choudhary1, Sanjiv Saigal1, Amey Sonavane1

  • 1Medanta Institute of Liver Transplantation and Regenerative Medicine, Medanta The Medicity, Gurgaon, Delhi (NCR), India.

Journal of Clinical and Experimental Hepatology
|September 14, 2019
PubMed

Mammalian target of rapamycin inhibitors (mTORis) are immunosuppression agents that are commonly used in solid organ transplantation. Available mTORis include sirolimus and everolimus. Interstitial lung disease (ILD) is an uncommon side effect of mTORis in liver transplantation. A high index of suspicion is needed, and timely intervention can reverse the disease. We present a case of sirolimus-induced ILD that improved after discontinuation of sirolimus.

Keywords:
HCC, hepatocellular carcinomaILD, Interstitial lung diseasedyspneainterstitial lung diseaseliver transplantationmTORi, Mammalian target of rapamycin inhibitorpulmonarysirolimus

More Related Videos

Orthotopic Left Lung Transplantation in Rats08:22

Orthotopic Left Lung Transplantation in Rats

Published on: July 3, 2025

644
Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation06:15

Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation

Published on: November 10, 2023

1.4K

Related Concept Videos

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Here, we present practical recommendations for performing thoracic high-resolution computed tomography for diagnosing and assessing systemic sclerosis-related interstitial lung...
20.8K
Orthotopic Left Lung Transplantation in Rats08:22

Orthotopic Left Lung Transplantation in Rats

This protocol describes an improved technique for orthotopic left lung transplantation in rats, focusing on reducing operational difficulty and improving survival...
644
Murine Intrapulmonary Tracheal Transplantation: A Model for Investigating Obliterative Airway Disease After Lung Transplantation06:15

Murine Intrapulmonary Tracheal Transplantation: A Model for Investigating Obliterative Airway Disease After Lung Transplantation

The murine intrapulmonary tracheal transplantation (IPTT) model is valuable for studying obliterative airway disease (OAD) after lung transplantation. It offers insights into lung-specific immunological and angiogenic behavior in airway obliteration after allotransplantation with high reproducibility. Here, we describe the IPTT procedure and its expected...
1.4K
Liver Cold Storage and Transplantation in the Cold-Adaptive Daurian Ground Squirrels08:37

Liver Cold Storage and Transplantation in the Cold-Adaptive Daurian Ground Squirrels

Here, we present a protocol to establish a long-term liver cold storage and transplantation model in Daurian ground squirrel (DGS), which has been technically challenging in standard rodent models.
743
Preservation of Porcine Donation after Circulatory Death (DCD) Liver by Perfusion and Orthotopic Liver Transplantation05:25

Preservation of Porcine Donation after Circulatory Death (DCD) Liver by Perfusion and Orthotopic Liver Transplantation

This protocol outlines the methodology of establishing a porcine model utilizing variable temperature-controlled Machine Perfusion (MP) for the preservation of the donor liver, followed by orthotopic liver transplantation (OLTx). It aims to promote the success rate of OLTx using donor donation after circulatory death (DCD) liver and establish a stable...
972
Intravital Two-Photon Microscopy of the Transplanted Mouse Lung04:16

Intravital Two-Photon Microscopy of the Transplanted Mouse Lung

Here, we present a protocol to intravitally image the transplanted mouse left lung using two-photon microscopy. This represents a valuable tool for studying cellular dynamics and interactions in real-time following murine lung transplantation.
1.7K