Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mistletoe Eradicator - A Novel Tool for Simultaneous Mechanical and Chemical Control of Mistletoe06:16

Mistletoe Eradicator - A Novel Tool for Simultaneous Mechanical and Chemical Control of Mistletoe

4.6K
The protocol describes an easy-to-handle tool called Mistletoe Eradicator which combines mechanical and chemical approaches and is efficient in the control of mistletoe infestation on the host trees. The manuscript uses the European mistletoe (Viscum album subsp. album L.) as an...
4.6K
Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules10:20

Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules

8.8K
3D single-molecule localization microscopy is utilized to probe the spatial positions and motion trajectories of fluorescently labeled proteins in living bacterial cells. The experimental and data analysis protocol described herein determines the prevalent diffusive behaviors of cytosolic proteins based on pooled single-molecule...
8.8K
Mechanical and Chemical Digestion in the Small Intestine01:30

Mechanical and Chemical Digestion in the Small Intestine

3.0K
The small intestine plays a crucial role in our digestive system, performing both mechanical and chemical digestion.
Mechanical digestion in the small intestine involves movements such as segmentations and migrating motility complexes (MMCs), primarily controlled by the myenteric plexus. Segmentations are localized contractions occurring in areas of the intestine distended by chyme—a mixture of partially digested food. These contractions mix chyme with digestive juices, facilitating...
3.0K
Characterizing Single-Molecule Conformational Changes Under Shear Flow with Fluorescence Microscopy08:47

Characterizing Single-Molecule Conformational Changes Under Shear Flow with Fluorescence Microscopy

6.3K
We present a protocol for immobilizing single macromolecules in microfluidic devices and quantifying changes in their conformations under shear flow. This protocol is useful for characterizing the biomechanical and functional properties of biomolecules such as proteins and DNA in a flow...
6.3K
Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers08:28

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers

8.6K
A single-molecule magnetic tweezers platform to manipulate G-quadruplexes is reported, which allows for the study of G4 stability and regulation by various...
8.6K
Chemical Agents for Microbial Control01:27

Chemical Agents for Microbial Control

766
Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
766

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Repulsive Gas-Electrode van der Waals Forces Enable Charge Transfer Reactions under Chemically Modified Bubbles.

Journal of the American Chemical Society·2026
Same author

Biomolecule Detection Methods Based on Nanoparticle Approaches.

ACS omega·2026
Same author

Di-chlorido-bis-(3-{[(pyridin-2-yl)methyl-idene]amino}-benzoic acid-κ<sup>2</sup> <i>N</i>,<i>N</i>')cobalt(II) methanol monosolvate monohydrate.

IUCrData·2026
Same author

Hair-raising: how carbon contamination can drive static charging.

Nature·2026
Same author

Polar Parallel Substituents Trigger High Conductance Paths in Carotenoid Wires.

ACS applied materials & interfaces·2026
Same author

A New Era for PPARγ: Covalent Ligands and Therapeutic Applications.

Journal of medicinal chemistry·2025

Related Experiment Video

Updated: Jan 19, 2026

Mistletoe Eradicator - A Novel Tool for Simultaneous Mechanical and Chemical Control of Mistletoe
06:16

Mistletoe Eradicator - A Novel Tool for Simultaneous Mechanical and Chemical Control of Mistletoe

Published on: March 1, 2022

4.6K

Chemically and Mechanically Controlled Single-Molecule Switches Using Spiropyrans.

Mark C Walkey, Chandramalika R Peiris1, Simone Ciampi1

  • 1School of Molecular Science and Curtin Institute of Functional Molecules and Interfaces , Curtin University , Bentley , WA 6102 , Australia.

ACS Applied Materials & Interfaces
|September 17, 2019
PubMed
Summary

Researchers created molecular circuits using spiropyran derivatives that act as diodes and respond to touch. These single-molecule devices offer a new path for developing responsive electronic components.

Keywords:
chemo-electronic switchesmechano-electronic switchesmolecular electronicssingle-molecule electronicssingle-molecule switches

More Related Videos

Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules
10:20

Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules

Published on: September 5, 2019

8.8K
Characterizing Single-Molecule Conformational Changes Under Shear Flow with Fluorescence Microscopy
08:47

Characterizing Single-Molecule Conformational Changes Under Shear Flow with Fluorescence Microscopy

Published on: January 25, 2020

6.3K

Related Experiment Videos

Last Updated: Jan 19, 2026

Mistletoe Eradicator - A Novel Tool for Simultaneous Mechanical and Chemical Control of Mistletoe
06:16

Mistletoe Eradicator - A Novel Tool for Simultaneous Mechanical and Chemical Control of Mistletoe

Published on: March 1, 2022

4.6K
Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules
10:20

Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules

Published on: September 5, 2019

8.8K
Characterizing Single-Molecule Conformational Changes Under Shear Flow with Fluorescence Microscopy
08:47

Characterizing Single-Molecule Conformational Changes Under Shear Flow with Fluorescence Microscopy

Published on: January 25, 2020

6.3K

Area of Science:

  • Molecular electronics
  • Organic electronics
  • Nanotechnology

Background:

  • Developing molecular circuits for electronic devices requires mechanical stability and responsiveness to stimuli.
  • Single-molecule circuits are key components for future miniaturized electronics.

Purpose of the Study:

  • To engineer single-molecule circuits with mechanical and chemical responsiveness.
  • To investigate the electrical properties of spiropyran derivatives as molecular electronic components.

Main Methods:

  • Fabrication of single-molecule junctions using spiropyran derivatives.
  • Electrical characterization of molecular circuits using scanning tunneling microscopy (STM).
  • Investigation of mechanical and chemical stimuli response.

Main Results:

  • Spiropyran derivatives exhibited single-molecule diode characteristics with a current rectification ratio of 5 at ±1 V.
  • Protonation of spiropyran formed a merocyanine state, showing diode behavior.
  • Mechanical pulling induced switching to a more conductive merocyanine state via C-O bond breaking.

Conclusions:

  • Spiropyran-based molecular circuits demonstrate electrical responsiveness to chemical and mechanical stimuli.
  • The study highlights the potential of spiropyran derivatives for creating switchable molecular electronic components.
  • Strong covalent bonding (Au-C) is crucial for mechanical switching in these molecular junctions.