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Designing for Accelerated Translation (DART) of Emerging Innovations in Health.

Alex T Ramsey1, Enola K Proctor2, David A Chambers3

  • 1Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.

Journal of Clinical and Translational Science
|September 19, 2019
PubMed
Summary
This summary is machine-generated.

This study introduces the DART framework to accelerate the translation of healthcare innovations into practice. It emphasizes dynamic decision-making based on evolving evidence, demand, risk, and cost for faster implementation.

Keywords:
designing for dissemination and implementationimplementation sciencelearning health systemprecision medicinespeed of translationstakeholder partnerships

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Area of Science:

  • Healthcare innovation translation
  • Dissemination and Implementation (D&I) research
  • Health services research

Background:

  • Dissemination and Implementation (D&I) research has advanced but primarily focuses on established practices.
  • There is a need to accelerate the translation of novel healthcare innovations.
  • Current D&I research often lags behind the pace of innovation.

Purpose of the Study:

  • To present a conceptual architecture for speeding the translation of promising innovations.
  • To clarify decision-making regarding acting on evolving evidence in healthcare.
  • To introduce the DART framework for dynamic evidence translation.

Main Methods:

  • Development of a conceptual framework (DART) for evidence translation.
  • Integration of evolving evidence with factors like demand, risk, and cost.
  • Emphasis on dynamic decision-making for innovation adoption and de-implementation.

Main Results:

  • The DART framework suggests acting on moderately uncertain, evolving evidence is feasible.
  • Incorporating demand, risk, and cost alongside evidence influences translation pace.
  • The framework facilitates decisions on adopting new or de-implementing suboptimal interventions.

Conclusions:

  • Accelerating innovation translation requires dynamic decision-making beyond just evidence certainty.
  • The DART framework provides a structured approach to speed evidence-to-practice movement.
  • Key actions include stakeholder partnerships, D&I-focused design, and learning health systems.