Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Using native human sera to assess the suitability of external quality assessment materials based on testosterone, progesterone, and 17β-estradiol measurements.

Frontiers in molecular biosciences·2026
Same author

Impact of the manufacturing process on the commutability of erythropoietin control materials for external quality assessment schemes.

Frontiers in molecular biosciences·2026
Same author

Cytokine Adsorption During Ex Vivo Blood Perfusion Improves Contractility of Donation After Circulatory Death Hearts.

Journal of the American Heart Association·2024
Same author

Investigations into the Concentrations and Metabolite Profiles of Doping Agents and Antidepressants in Human Seminal Fluid Using Liquid Chromatography-Mass Spectrometry.

Drug metabolism and disposition: the biological fate of chemicals·2024
Same author

Experiences and challenges for EQA providers in assessing the commutability of control materials in accuracy-based EQA programs.

Frontiers in medicine·2024
Same author

Evaluation of university and training standards in clinical perfusion, an European-wide survey.

Interdisciplinary cardiovascular and thoracic surgery·2024

Related Experiment Video

Updated: Jan 19, 2026

Separation and Identification of Conventional Microplastics from Farmland Soils
14:10

Separation and Identification of Conventional Microplastics from Farmland Soils

Published on: March 21, 2025

3.1K

Validation of an extraction method for microplastics from human materials.

Adrian Monteleone1, Weronika Schary1, Andreas Fath1

  • 1Faculty of Medical and Life Sciences, Hochschule Furtwangen, Germany.

Clinical Hemorheology and Microcirculation
|September 29, 2019
PubMed
Summary

A new method effectively extracts microplastic particles from human and animal tissues. This validated technique allows for reliable detection and quantification of microplastics, ensuring minimal impact on the plastic materials themselves.

Keywords:
Microplasticextraction methodhuman tissuemicroparticel

More Related Videos

Extraction of Organochlorine Pesticides from Plastic Pellets and Plastic Type Analysis
10:12

Extraction of Organochlorine Pesticides from Plastic Pellets and Plastic Type Analysis

Published on: July 1, 2017

12.1K
Sampling and Identification of Microplastics in Groundwater
08:27

Sampling and Identification of Microplastics in Groundwater

Published on: November 7, 2025

977

Related Experiment Videos

Last Updated: Jan 19, 2026

Separation and Identification of Conventional Microplastics from Farmland Soils
14:10

Separation and Identification of Conventional Microplastics from Farmland Soils

Published on: March 21, 2025

3.1K
Extraction of Organochlorine Pesticides from Plastic Pellets and Plastic Type Analysis
10:12

Extraction of Organochlorine Pesticides from Plastic Pellets and Plastic Type Analysis

Published on: July 1, 2017

12.1K
Sampling and Identification of Microplastics in Groundwater
08:27

Sampling and Identification of Microplastics in Groundwater

Published on: November 7, 2025

977

Area of Science:

  • Environmental Science
  • Analytical Chemistry
  • Toxicology

Background:

  • Global plastic production has surged since 1950, leading to widespread environmental microplastic contamination.
  • Microplastics are increasingly detected in the environment, raising concerns about potential human uptake.
  • This study addresses the critical need to detect microplastic particles within biological organisms.

Purpose of the Study:

  • To develop and validate an extraction method for detecting microplastic particles in human and animal biological samples.
  • To assess the impact of the extraction process on the integrity of various plastic types.
  • To establish a reliable method for quantifying microplastic contamination in biological tissues.

Main Methods:

  • Human blood and animal tissues were used as biological matrices.
  • Various lysis solutions were tested for their efficiency in degrading biological material and their effect on plastics.
  • Atomic force microscopy (AFM), electron microscopy (EM), and Fourier transform infrared spectrometry (FTIR) were employed for analysis.

Main Results:

  • Fourier transform infrared spectrometry (FTIR) successfully differentiated and identified plastic types including polyamide (PA), polycarbonate (PC), polyethylene (PE), polypropylene (PP), polystyrene (PS), and polyvinyl chloride (PVC).
  • Polyvinyl chloride (PVC) exhibited surface alterations post-extraction, such as irregular structures.
  • The method demonstrated a high overall recovery rate of 99.12±0.67%, indicating efficient particle retrieval.

Conclusions:

  • The developed extraction method is effective for isolating microplastics from human and animal tissues.
  • The method ensures minimal alteration to the plastic particles, preserving their integrity for analysis.
  • This validated technique provides a reliable tool for studying microplastic exposure in biological systems.