Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

375
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
375
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

13.2K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.2K
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

3.5K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
3.5K
Comparing the Survival Analysis of Two or More Groups01:20

Comparing the Survival Analysis of Two or More Groups

525
Survival analysis is a cornerstone of medical research, used to evaluate the time until an event of interest occurs, such as death, disease recurrence, or recovery. Unlike standard statistical methods, survival analysis is particularly adept at handling censored data—instances where the event has not occurred for some participants by the end of the study or remains unobserved. To address these unique challenges, specialized techniques like the Kaplan-Meier estimator, log-rank test, and...
525

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Leveraging Social Media in Underrepresented Populations: A Cross-Sectional Study.

Urogynecology (Philadelphia, Pa.)·2026
Same author

The Effect of Shift Timing on Cesarean Delivery Outcomes and Operative Noise Levels.

American journal of perinatology·2024
Same author

The Impact of Environmental and Occupational Noise on Maternal and Perinatal Pregnancy Outcomes.

Obstetrical & gynecological survey·2024
Same author

Enabling Technologies for Gynecologic Vaginal Surgery: A Systematic Review.

Obstetrics and gynecology·2024
Same author

Urticaria Multiforme.

The Journal of pediatrics·2023
Same author

Noise in cesarean deliveries: a comprehensive analysis of noise environments in the Labor and Delivery operating room and evaluation of a visual alarm noise abatement program.

American journal of obstetrics & gynecology MFM·2023
Same journal

Antenatal Testing Education: Assessing Health Education and Health Knowledge in a High-Risk Pregnant Population.

AJP reports·2026
Same journal

Cross-Sectional Survey of Obstetrical Providers' Knowledge, Attitudes, and Use of Noninvasive Prenatal Testing for 22q11.2 Deletion.

AJP reports·2026
Same journal

Obligate Funic Presentation: A Case Report of Velamentous Cord Insertion in a Normally Implanted Placenta.

AJP reports·2026
Same journal

Refractory Neonatal Apnea Revealing Congenital Central Hypoventilation Syndrome: Improved Outcome through Early Multidisciplinary Intervention.

AJP reports·2026
Same journal

Congenital Thrombocytosis, Hepatosplenomegaly, and Rash in a Term Neonate.

AJP reports·2026
Same journal

Concordant Open Neural Tube Defects in a Monochorionic Twin Pair of a Dichorionic-Triamniotic Triplet Gestation.

AJP reports·2026
See all related articles

Related Experiment Video

Updated: Jan 6, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization
10:19

A Murine Model of Group B Streptococcus Vaginal Colonization

Published on: November 16, 2016

14.9K

Universal versus Risk-Based Management of Unknown Group B Streptococcus Status at Term.

Danielle M Jones1, Samantha O Haikal2, Megan D Whitham3

  • 1School of Medicine, University of Nevada, Las Vegas, Las Vegas, Nevada.

AJP Reports
|October 4, 2019
PubMed
Summary
This summary is machine-generated.

Universal intrapartum antibiotic prophylaxis (IAP) for Group B streptococcus (GBS) may be more cost-effective than risk-based strategies. This approach can reduce healthcare costs by minimizing extended hospital stays for mothers and newborns.

Keywords:
early-onset Group B streptococcus (EOGBS)intrapartum antibiotic prophylaxismaternal intrapartum feverneonatal sepsisprelabor rupture of membranesrisk-based management of GBSuniversal management of GBS

More Related Videos

Author Spotlight: Accelerating Diagnostic Accuracy with Direct Identification of Gram-Negatives from Blood Culture Bottles
09:07

Author Spotlight: Accelerating Diagnostic Accuracy with Direct Identification of Gram-Negatives from Blood Culture Bottles

Published on: May 24, 2024

1.4K
Genotyping of Staphylococcus aureus by Ribosomal Spacer PCR RS-PCR
08:51

Genotyping of Staphylococcus aureus by Ribosomal Spacer PCR RS-PCR

Published on: November 4, 2016

10.1K

Related Experiment Videos

Last Updated: Jan 6, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization
10:19

A Murine Model of Group B Streptococcus Vaginal Colonization

Published on: November 16, 2016

14.9K
Author Spotlight: Accelerating Diagnostic Accuracy with Direct Identification of Gram-Negatives from Blood Culture Bottles
09:07

Author Spotlight: Accelerating Diagnostic Accuracy with Direct Identification of Gram-Negatives from Blood Culture Bottles

Published on: May 24, 2024

1.4K
Genotyping of Staphylococcus aureus by Ribosomal Spacer PCR RS-PCR
08:51

Genotyping of Staphylococcus aureus by Ribosomal Spacer PCR RS-PCR

Published on: November 4, 2016

10.1K

Area of Science:

  • Obstetrics and Gynecology
  • Public Health Economics
  • Infectious Disease Prevention

Background:

  • Group B Streptococcus (GBS) screening and prophylaxis are critical in preventing neonatal infections.
  • Current risk-based strategies for intrapartum antibiotic prophylaxis (IAP) may lead to prolonged hospitalizations.
  • Unknown GBS status at term presents a challenge for optimal maternal and neonatal care.

Purpose of the Study:

  • To estimate and compare the public health costs of universal versus risk-based IAP administration for women with unknown GBS status.
  • To evaluate the economic impact of different IAP strategies on healthcare systems.
  • To determine the most cost-effective approach for GBS prevention in term deliveries.

Main Methods:

  • Estimation of the annual number of women in the U.S. meeting specific criteria (unscreened, no risk factors, vaginal delivery, multiparous, early discharge eligibility).
  • Modeling of costs associated with risk-based strategy (additional 24-hour observation stay).
  • Modeling of costs associated with universal IAP (penicillin cost, early discharge).

Main Results:

  • Risk-based management for unscreened women without rupture of membranes (>18 hours) ranged from $468M to $850M.
  • Risk-based management for unscreened women without maternal intrapartum fever ranged from $742M to $919M.
  • Universal IAP administration costs ranged from $470M to $568M, showing cost equivalence or reduction.

Conclusions:

  • Universal IAP administration may be more cost-saving compared to risk-based strategies.
  • Cost reductions of up to 33.2% were observed with universal IAP.
  • Reduced extended hospitalizations for neonates and mothers contribute to the cost-effectiveness of universal IAP.