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[Primary pseudo-ovarian peritoneal carcinosis. 4 cases]
Presse Medicale (Paris, France : 1983)
|March 30, 1985
Summary
Primary papillary carcinosis of the peritoneum is a rare cancer in older women. Effective chemotherapy, similar to ovarian cancer treatment, can achieve remission, but relapses occur.
Area of Science:
- Gynecologic Oncology
- Pathology
- Surgical Oncology
Background:
- Primary papillary carcinosis of the peritoneum (PPCP) is a rare malignancy.
- It primarily affects elderly women and mimics advanced ovarian cancer.
- Histologically, PPCP is indistinguishable from papillary ovarian carcinoma.
Observation:
- Four cases of PPCP were treated as advanced ovarian carcinomas.
- Treatment involved multi-agent chemotherapy, including doxorubicin and cisplatin.
- Patients underwent re-operation after six chemotherapy courses.
Findings:
- Complete remission was achieved in all four patients.
- However, all patients relapsed during maintenance therapy.
- This highlights the aggressive nature of the disease despite initial response.
Implications:
- Early suspicion of PPCP is crucial in elderly women with unexplained carcinosis.
- Prompt diagnosis allows for timely and effective treatment, comparable to advanced ovarian cancer.
- Further research into novel maintenance therapies is warranted to prevent relapse.