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Published on: December 22, 2020
Two new alcohol glycosides from the roots of Paeonia intermedia C. A. Meyer
Liang Yu1, Ling-Juan Zhu1,2, An-Hua Wang1
1School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
Abstract:
Two new alcohol glycosides, 1-O-β-d-glucopyranosyl-deoxypaeonisuffrone (1) and 9-O-β-d-apiofuranoyl-(1→6)-β-d-glucopyranosyl-xanthoarnol (2), together with eight known compounds (3-10), have been isolated from the dried roots of Paeonia intermedia C. A. Meyer. Their structures were mainly elucidated on the basis of ESIMS, one- and two-dimensional NMR techniques. Antibacterial activities of compounds 1-10 were evaluated, and compounds 9 and 10 showed antibacterial activities against Staphylococcus argenteus CMCC26003 and Escherichia coli CMCC44103. [Formula: see text].
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