Related Experiment Video
Updated: Jan 5, 2026

Cell Population Analyses During Skin Carcinogenesis
Published on: August 21, 2013
Recurrence of linear basal cell carcinoma
Jordan Maxwell Ward1, Mark Russell2
1Department of Medicine, Augusta University, Georgia, USA.
Linear basal cell carcinoma (LBCC) is a rare, high-risk skin cancer variant. Early detection and complete margin assessment, such as Mohs surgery, are crucial for treating recurrent LBCC effectively.
Area of Science:
- Dermatology
- Oncology
Background:
- Linear basal cell carcinoma (LBCC) is an uncommon morphologic subtype of basal cell carcinoma.
- Recurrence of LBCC necessitates understanding its high-risk nature and optimal treatment strategies.
Observation:
- A case study details a patient with recurrent LBCC on the supraclavicular neck following prior excision and repeated mild trauma.
- Literature review summarizes demographics, location, histology, treatments, and recurrence rates of reported LBCC cases.
Findings:
- LBCC is identified as a high-risk subtype due to potential subclinical spread.
- Recurrence is a significant concern in managing LBCC.
Implications:
- Mohs micrographic surgery or complete peripheral and deep margin assessment excisions are recommended as first-line treatments for LBCC.
- Recognizing LBCC as high-risk guides clinical management and improves patient outcomes.
More Related Videos
09:37Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
06:15Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Renewal of Skin Epidermal Stem Cells
Tumor Progression
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Cancers Originate from Somatic Mutations in a Single Cell
The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
Cancer Stem Cells and Tumor Maintenance
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...