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    Area of Science:

    • Biomedical Engineering
    • Wearable Technology
    • Sensor Systems

    Background:

    • Existing wearable devices often lack continuous monitoring capabilities, particularly for blood pressure.
    • Physiological sensing systems require robust noise-immune architectures for accurate data acquisition.
    • Integration of multiple sensing modalities into a single wearable system presents significant engineering challenges.

    Purpose of the Study:

    • To develop a flexible, multi-functional physiological sensing system with hybrid-sensing capabilities.
    • To enable continuous blood pressure monitoring using a wearable device.
    • To reduce the post-processing burden of hybrid sensing methods through analog pre-processing.

    Main Methods:

    • Utilized an in-house multi-functional e-skin device, flexible electrodes, and a LED-photodiode pair.
    • Integrated five physiological detection methodologies: piezo-resistive, pyro-resistive, electro-metric, opto-metric, and hybrid.
    • Developed a single readout integrated circuit (ROIC) with three readout paths (two electrometric, one impedometric) and implemented noise-immune techniques.

    Main Results:

    • Demonstrated eight representative physiological detection capabilities using wearable prototypes.
    • Achieved innovative continuous blood pressure measurement, a significant advancement over previous wearable devices.
    • Successfully reduced the post-processing burden for blood pressure estimation via an analog pre-processing scheme.

    Conclusions:

    • The proposed flexible multi-functional sensing system offers a robust platform for advanced wearable health monitoring.
    • The hybrid sensing capability, particularly for continuous blood pressure monitoring, represents a key innovation.
    • The integrated analog pre-processing scheme enhances the practicality and efficiency of wearable physiological sensing systems.