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Updated: Jan 5, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[The surgical effect on obstructive sleep apnea with laryngopharyngeal reflux]
Abstract:
Objective:To explore the effect of surgical treatment for OSA with laryngopharyngeal reflux(LPR). Method:A retrospective analysis was made in 42 patients diagnosed as moderate to severe OSA with LPR and treated with modified-coblation assisted Uvulopalatopharyngoplasty(M-CAUP). The results of PSG, reflux symptom index(RSI), reflux finding score(RFS) and 24-hour esophageal pH monitoring before and after operation were compared. Result:The AHI after operation was significantly lower than that before operation(P<0.05), and the average oxygen saturation and minimum blood pressure saturation were increased(P<0.05). The total scores of RSI and RFS after operation were lower than those before operation(P<0.05). The percentage of time of pH<4.0 in esophagus 24 hours after operation was lower than that before operation(P<0.05). Conclusion:For patients with moderate to severe OSA combined with LPR with oropharyngeal obstruction, surgical treatment can not only reduce airway stenosis and obstruction, but also improve the symptoms and signs of LPR.
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