Abstract 10613: Symptomatic Human Immunodeficiency Virus Infected Patients Receive Less Aggressive Revascularization...

Area of Science:

• Cardiology
• Infectious Diseases
• Public Health

Background:

• Cardiovascular disease (CVD) is a major cause of death in adults with human immunodeficiency virus (HIV).
• Previous research suggests disparities in Acute Coronary Syndrome (ACS) treatment for HIV patients.
• Aggressive management of CVD in HIV-infected adults is recommended.

Purpose of the Study:

• To investigate treatment disparities in cardiac revascularization procedures for HIV-infected patients diagnosed with ACS.
• To compare procedural rates among symptomatic HIV, asymptomatic HIV, and control groups.
• To utilize recent, large-scale cohort data for comprehensive analysis.

Main Methods:

• Retrospective review of the Nationwide Inpatient Sample (NIS) database from 2013 to 2016.
• Identification of patients with ACS (ST-elevation myocardial infarction, non-ST-elevation myocardial infarction, unstable angina).
• Comparison of cardiac catheterization, Percutaneous Coronary Intervention (PCI), and Coronary Artery Bypass Graft (CABG) rates across control, asymptomatic HIV, and symptomatic HIV groups using multivariate regression.

Main Results:

• A total of 515,016 ACS patients were identified; 2066 (0.40%) had an HIV diagnosis.
• Symptomatic HIV patients with ACS showed significantly lower rates of catheterization (OR: 0.62), PCI (OR: 0.80), and CABG (OR: 0.70) compared to controls.
• Asymptomatic HIV patients with ACS did not exhibit significant differences in procedural rates compared to controls.

Conclusions:

• A significant treatment disparity exists for symptomatic HIV-infected patients experiencing ACS, with reduced rates of aggressive cardiac management.
• This disparity in catheterization and revascularization procedures was not observed in asymptomatic HIV patients with ACS.
• Findings highlight the need for equitable cardiovascular care for all individuals living with HIV.