Hypertrophic cardiomyopathy masked by pericarditis

Area of Science:

• Cardiology
• Genetics
• Pathology

Background:

• Hypertrophic cardiomyopathy (HCM) was historically viewed as a rare, untreatable cause of sudden death, primarily in young male athletes.
• Recent advancements recognize HCM as an increasingly prevalent and treatable familial disease.

Observation:

• This case report details a middle-aged female patient with hereditary hypertrophic cardiomyopathy.
• The condition was masked by superimposed pericarditis, leading to a delayed diagnosis.
• Autopsy revealed the underlying familial hypertrophic cardiomyopathy.

Findings:

• Co-morbidity, such as pericarditis, can obscure the diagnosis of hypertrophic cardiomyopathy.
• Autopsy played a crucial role in identifying the familial nature of the disease.
• Hypertrophic cardiomyopathy is significantly more treatable today than in the past.

Implications:

• Early diagnosis of hypertrophic cardiomyopathy is vital for preventing sudden cardiac death.
• Healthcare providers must consider hypertrophic cardiomyopathy in female patients, irrespective of age or athletic status.
• Autopsy remains a valuable tool for uncovering familial diseases and improving patient care strategies.