Recovery of the diffuse correlation spectroscopy data-type from speckle contrast measurements: towards low-cost,
K Murali1, A K Nandakumaran2, Turgut Durduran3,4
1Department of Biosciences and Bioengineering, Indian Institute of Technology - Bombay (IITB), India.
Biomedical Optics Express
|October 25, 2019
Abstract:
A multi-step Volterra integral equation-based algorithm was developed to measure the electric field auto-correlation function from multi-exposure speckle contrast data. This enabled us to derive an estimate of the full diffuse correlation spectroscopy data-type from a low-cost, camera-based system. This method is equally applicable for both single and multiple scattering field auto-correlation models. The feasibility of the system and method was verified using simulation studies, tissue mimicking phantoms and subsequently in in vivo experiments.
