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Intermediate Uveitis as the Initial and Only Presentation of Syphilis
Sevcan Yıldız Balcı1, Ece Turan Vural1, Şehnaz Özçalışkan2
1University of Health Sciences, Haydarpaşa Numune Training and Research Hospital, Ophthalmology Clinic, İstanbul, Turkey
Syphilis can cause eye inflammation (intermediate uveitis) even without other symptoms. Early diagnosis is crucial for vision preservation, even with atypical presentations.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Immunology
Background:
- Syphilis, a complex infectious disease, can manifest with diverse ocular complications.
- Ocular syphilis requires high clinical suspicion due to varied presentations.
Observation:
- A patient presented with unilateral intermediate uveitis and cystoid macular edema in the left eye.
- The patient had no concurrent dermatological, neurological, or systemic signs of syphilis.
Findings:
- Serological tests, including the Venereal Disease Research Laboratory (VDRL) and Treponema pallidum microhemagglutination assay (MHA-TP), confirmed syphilis.
- The ocular findings were isolated to the left eye, indicating a unilateral presentation.
Implications:
- Syphilitic uveitis should be considered in cases of unexplained ocular inflammation.
- Prompt diagnosis and treatment are essential to prevent vision loss in ocular syphilis.
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