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Updated: Jan 4, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

Modern Brachytherapy.

Sophie J Otter¹, Alexandra J Stewart¹, Phillip M Devlin²

¹Royal Surrey County Hospital, Egerton Road, Guildford GU2 7XX, UK.

Hematology/Oncology Clinics of North America

|November 1, 2019

Summary

This summary is machine-generated.

Brachytherapy uses internal radioactive sources for precise cancer treatment, sparing healthy tissue. Modern advancements enhance safety, accuracy, and adaptability in treating various cancers.

Keywords:

Brachytherapy Breast cancer Cervix cancer Normal tissue sparing Prostate cancer Radionuclide Rectal cancer Skin cancer

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Area of Science:

Oncology
Radiation Oncology
Medical Physics

Background:

Brachytherapy delivers radiotherapy directly to tumors using internal radioactive sources.
This method maximizes radiation dose to the tumor while minimizing exposure to surrounding healthy tissues.
Technological advancements have significantly improved brachytherapy delivery and applications.

Purpose of the Study:

To explore the most modern techniques in brachytherapy.
To review the current applications of brachytherapy across various cancer types.
To highlight advancements in radioactive sources, image guidance, and planning systems.

Main Methods:

Review of modern brachytherapy techniques.
Analysis of current clinical uses in gynecological, prostate, breast, rectal, and skin cancers.
Discussion of advancements in radioactive sources, image guidance, and adaptive planning.

Main Results:

Newer radioactive sources improve the safety of brachytherapy delivery.
Image guidance techniques enhance the precision of radioactive source placement.
Advanced planning systems enable truly adaptive brachytherapy treatments.

Conclusions:

Brachytherapy is a continuously evolving radiotherapy technique.
Modern brachytherapy offers safer, more accurate, and adaptive treatment options.
It remains a crucial modality for treating gynecological, prostate, breast, rectal, and skin cancers.