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Published on: October 21, 2017
Nutrition in Chronic Liver Disease
Yala Kirthi Reddy1, Benedict Maliakkal2,3, Uchenna Agbim4,5
1Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Malnutrition in chronic advanced liver disease (CLD) requires assessing nutrient intake, sarcopenia, and frailty. Early interventions are crucial for improving outcomes and halting muscle loss in CLD patients.
Area of Science:
- Hepatology
- Clinical Nutrition
- Geriatrics
Background:
- Malnutrition is prevalent in chronic advanced liver disease (CLD), significantly impacting patient morbidity and mortality.
- Nutritional status in CLD is complex, influenced by nutrient intake, muscle mass (sarcopenia), and overall physical condition (frailty).
Purpose of the Study:
- To review current evidence-based guidelines and expert opinions on diagnosing malnutrition in CLD patients.
- To outline optimal strategies for managing malnutrition and related conditions in CLD.
Main Methods:
- Systematic review of recent literature.
- Synthesis of expert consensus and clinical guidelines.
Main Results:
- Nutritional assessment in CLD must integrate nutrient intake, sarcopenia, and frailty.
- Interventions targeting sarcopenia and frailty are as vital as nutritional supplementation.
- Early detection and intervention during compensated cirrhosis can yield significant benefits.
Conclusions:
- Optimal management of malnutrition in CLD necessitates a holistic approach addressing nutritional status, muscle mass, and functional capacity.
- Vigilance and early intervention are key to maximizing nutritional gains and preventing muscle loss in the early stages of CLD.
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