Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Lampbrush Chromosomes01:51

Lampbrush Chromosomes

8.5K
In 1882, Flemming observed lampbrush chromosomes (LBC) in salamander eggs. Later in 1892, Rückert observed LBCs in shark egg cells and coined the term "lampbrush chromosomes" because they looked like brushes used to clean kerosene lamps.
LBCs are made up of two pairs of conjugating homologous chromatids. Each chromatid consists of alternatively positioned regions of condensed-inactive chromatin and loosely placed-active side loops, which can be contracted and extended. The loops...
8.5K
Structure and Organization of Smooth Muscles01:13

Structure and Organization of Smooth Muscles

8.3K
Smooth muscle tissue is a type of muscle tissue that can be found lining various vital organs in the human body, including the lungs, blood vessels, digestive tract, and respiratory tract. This type of tissue is responsible for regulating the movements of these organs, playing crucial roles in the functioning of various systems, including the vascular, digestive, respiratory, and urinary systems.
Structure of smooth muscle cell
Smooth muscle cells are spindle-shaped with tapering ends and a...
8.3K
Skin Cancer01:30

Skin Cancer

5.6K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.6K
Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

8.7K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
8.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Total disc replacement versus lumbar interbody fusion for degenerative disc disease: a meta-analysis of randomized controlled trials.

Neurosurgical focus·2026
Same author

Full Endoscopic versus Microscopic Lumbar Discectomy for Lumbar Disc Herniation: A Meta-analysis of Randomized-controlled Trials.

Spine·2026
Same author

Real-World Evidence of Treatment Patterns, Time to Real-World Progression, and Overall Survival of Patients With Testicular Germ Cell Tumors Receiving Palliative Chemotherapy in the United States.

Cancer medicine·2026
Same author

Predicting cage subsidence after lumbar interbody fusion: a meta-analysis of opportunistic bone quality metrics.

The spine journal : official journal of the North American Spine Society·2026
Same author

Mean Arterial Pressure Augmentation for Acute Traumatic Spinal Cord Injury: A Systematic Review and Meta-Analysis of Neurological Recovery and Mortality.

Global spine journal·2026
Same author

Diagnostic performance of machine learning models versus established risk stratification for intracranial aneurysm rupture: a systematic review and bivariate meta-analysis.

Journal of neurology, neurosurgery, and psychiatry·2026
Same journal

Post-extubation pneumothorax following bougie-assisted endotracheal tube exchange.

BMJ case reports·2026
Same journal

Cardiac tamponade secondary to hypothyroidism.

BMJ case reports·2026
Same journal

Unmasking a rare contrast reaction: acute non-cardiogenic pulmonary oedema after iohexol injection.

BMJ case reports·2026
Same journal

Water gonioscopy-assisted transluminaltrabeculotomy.

BMJ case reports·2026
Same journal

<i>Clostridioides difficile</i> osteomyelitis presenting as a Brodie's abscess of the tibia.

BMJ case reports·2026
Same journal

Steroid refractory rapidly progressing organising pneumonia.

BMJ case reports·2026
See all related articles

Related Experiment Video

Updated: Jan 4, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
07:36

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

14.8K

Exceptionally large, atypically located spindle cell lipoma.

Mitchell John1, Shaan Patel1, George Joseph1,2

  • 1Department of Orthopaedic Surgery, University of South Florida, Tampa, Florida, USA.

BMJ Case Reports
|November 3, 2019
PubMed
Summary
This summary is machine-generated.

Spindle cell lipomas are rare benign tumors. This report details the largest spindle cell lipoma of the hand ever documented, measuring 11 cm, presenting a unique clinical case.

Keywords:
oncologyorthopaedics

More Related Videos

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
08:57

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

2.5K

Related Experiment Videos

Last Updated: Jan 4, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
07:36

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

14.8K
Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
08:57

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

2.5K

Area of Science:

  • Surgical pathology
  • Orthopedic oncology
  • Dermatopathology

Background:

  • Spindle cell lipomas (SCLs) are rare, benign soft tissue tumors.
  • Typically found in the shoulder/neck region of middle-aged men.
  • Histologically characterized by mature adipocytes, collagen, and spindle cells.

Observation:

  • A 54-year-old male presented with a large left palm mass causing discomfort and paresthesia.
  • Radiographs revealed a radiolucent mass; MRI showed a lipomatous mass encasing flexor tendons.
  • The mass measured 11 cm × 7 cm × 4 cm.

Findings:

  • Excisional biopsy and immunohistological analysis confirmed spindle cell lipoma.
  • This represents the largest SCL of the hand reported in medical literature.
  • It is also the largest SCL described in the upper extremity.

Implications:

  • Highlights the potential for SCLs to occur in atypical locations and reach significant sizes.
  • Emphasizes the importance of thorough histopathological examination for large or unusually located lipomas.
  • Contributes to the understanding of the spectrum of SCL presentation and size variations.