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Published on: January 29, 2016
Independent outdoor mobility of persons with multiple sclerosis - A systematic review
F E van der Feen1, G A de Haan1, I van der Lijn1
1Clinical and Developmental Neuropsychology, University of Groningen, Grote Kruisstraat 1/2, 9712 TS Gronigen, the Netherlands; Royal Dutch Visio, Centre of Expertise for Blind and Partially Sighted People, PO box 1180, 1270 BD Huizen, the Netherlands.
Background:
Multiple sclerosis (MS) can manifest itself in many ways, all of which can affect the independent outdoor mobility of persons with MS (pwMS). In most studies, mobility of pwMS is defined by the ability to walk. However, mobility comprises more than walking alone. This systematic review provides an overview of the literature on several types of independent outdoor mobility of pwMS. We aimed to identify which specific factors may influence outdoor mobility and how the lives of pwMS may be affected by a reduced mobility.
Methods:
A systematic literature search was performed, using three databases (PubMed, PsychInfo and Web of Science). Studies had to describe a group of pwMS sclerosis and had to concern some type of mobility other than walking.
Results:
The 57 studies that fulfilled the criteria included in total 10,394 pwMS and in addition, 95,300 pwMS in separate prevalence study. These studies showed that pwMS as a group have a decreased fitness to drive, make use of a wheelchair or mobility scooter more often and have difficulties making use of public transport. Mobility problems especially occur in patients with cognitive problems, secondary progressive MS or high disability scores.
Conclusions:
The reduced mobility may prevent pwMS participating in society. However, few studies investigating interventions or rehabilitation options to improve mobility were found in the existing literature, highlighting an until now under recognised unmet need.
Insights
Multiple sclerosis (MS) significantly impacts outdoor mobility beyond walking for persons with MS (pwMS). Reduced mobility affects societal participation, with limited research on interventions.
Area of Science:
- Neurology
- Rehabilitation Science
- Mobility Studies
Background:
- Multiple sclerosis (MS) presents diverse challenges affecting independent outdoor mobility in persons with MS (pwMS).
- Existing research often narrowly defines mobility as walking, overlooking broader aspects.
- This review synthesizes literature on various forms of outdoor mobility for pwMS.
Purpose of the Study:
- To identify factors influencing independent outdoor mobility in pwMS.
- To understand the impact of reduced mobility on the lives of pwMS.
- To explore mobility types beyond walking in the context of MS.
Main Methods:
- A systematic literature search was conducted across PubMed, PsychInfo, and Web of Science.
- Included studies focused on groups of pwMS and mobility types other than walking.
- 57 studies involving 10,394 pwMS were analyzed, with additional prevalence data from 95,300 pwMS.
Main Results:
- PwMS demonstrate reduced driving fitness and increased reliance on wheelchairs or mobility scooters.
- Difficulties were noted in utilizing public transportation.
- Mobility impairments are more pronounced in individuals with cognitive issues, secondary progressive MS, or high disability scores.
Conclusions:
- Reduced outdoor mobility can hinder societal participation for pwMS.
- There is a significant gap in research on interventions and rehabilitation strategies to improve mobility.
- This highlights an under-recognized unmet need in MS care.

