[Autoimmune hepatitis and pregnancy: a case series]

Area of Science:

• Hepatology
• Immunology
• Obstetrics

Background:

• Autoimmune hepatitis (AIH) is a chronic liver disease requiring long-term management.
• Pregnancy in women with chronic liver conditions presents unique clinical challenges.
• Immunosuppressive therapy is standard for AIH but its safety during pregnancy requires careful consideration.

Observation:

• Four female patients with AIH were treated between 2014-2018.
• These patients conceived and carried pregnancies to term while on immunosuppressive treatment.
• The liver unit of the National Hospital Arzobispo Loayza managed these cases.

Findings:

• All four pregnancies resulted in uncomplicated outcomes.
• Patients continued their immunosuppressive treatment throughout their pregnancies.
• The study documents the sequence of events and clinical outcomes.

Implications:

• Immunosuppressive treatment for autoimmune hepatitis appears safe during pregnancy.
• Successful pregnancy outcomes are achievable for women with AIH on treatment.
• This case series contributes to understanding AIH management in pregnant patients.