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Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
Published on: July 21, 2011
Synthesis of homoleptic, divalent lanthanide (Sm, Eu) complexes via oxidative transmetallation
Thaige P Gompa1, Ningxin Jiang1, John Bacsa1
1Department of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332-0400, USA. hsl@gatech.edu.
Abstract:
The direct synthesis of neutral, divalent samarium and europium complexes supported by the bulky bis(tris-tert-butoxysilyl)amide (BTTSA) ligand via oxidative transmetallation is reported. Through the use of a copper(i) ligand complex, conventional lanthanide halide starting materials for complex formation are circumvented and the clean formation of divalent complexes is achieved directly from the bulk metal. The structures of the [Ln(BTTSA)2] (Ln = Sm, Eu) complexes are isotypic, presenting divalent lanthanide ions with distorted, six-coordinate geometries.
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