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Updated: Jan 4, 2026
Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
Published on: July 16, 2014
Deep Brain Stimulation in Parkinsons Disease in Nepal
R Shrestha1, T Taira2, P Shrestha1
1Department of Neurosurgery, Annapurna Neurological Institute and Allied Sciences, Kathmandu, Nepal.
Deep Brain Stimulation shows promising results for treating Parkinson's disease motor symptoms in Nepal. While effective, the treatment is costly and requires ongoing neuromodulation management.
Area of Science:
- Neurology
- Neurosurgery
Background:
- Parkinson's disease is a neurodegenerative disorder impacting motor function.
- Surgical interventions target altered basal ganglia-thalamocortical circuits.
- Pallidotomy and Deep Brain Stimulation are current surgical options.
Purpose of the Study:
- To evaluate the efficacy of Deep Brain Stimulation (DBS) for Parkinson's disease in Nepal.
Main Methods:
- Ten patients with idiopathic Parkinson's disease underwent DBS surgery.
- Standard functional coordinates for Subthalamic Nucleus and Globus Pallidus Internus were utilized.
- Preoperative and postoperative Unified Parkinson's Disease Rating Scale, Hoehn and Yahr, and Schwab and England scales were assessed.
Main Results:
- Significant improvement in motor manifestations was observed post-DBS.
- Activities of daily living scores showed significant improvement.
- The study included a 2:1 male to female ratio, with a mean age of 55.4 years.
Conclusions:
- Deep Brain Stimulation presents a promising surgical option for Parkinson's disease in Nepal.
- High cost and the need for frequent neuromodulation follow-up are noted challenges.
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