Contrast-Induced Vomiting in Pediatric Patients Under Propofol Sedation: A Case Series

Area of Science:

• Radiology
• Pediatric Imaging
• Pharmacology

Background:

• Gadolinium-based contrast agents (GBCAs) are essential for MRI.
• Adverse events like nausea and vomiting are known but less studied in pediatric populations.
• Pediatric patients often require sedation for MRI, complicating adverse event management.

Observation:

• Three pediatric cases of vomiting post-GBCA administration during propofol sedation are presented.
• Propofol, typically having antiemetic properties, was used in these sedated patients.
• Vomiting occurred shortly after contrast administration.

Findings:

• Despite propofol's antiemetic properties, vomiting occurred in these pediatric patients.
• The adverse events resolved without lasting complications in all reported cases.
• This series underscores the potential for serious consequences of vomiting during sedation.

Implications:

• Healthcare providers should be vigilant for vomiting during pediatric sedation for MRI.
• Awareness of GBCA-associated emesis in sedated children is crucial.
• Further research may be needed to understand and mitigate these risks in pediatric procedural sedation.