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Updated: Jan 3, 2026

Multiplexing Focused Ultrasound Stimulation with Fluorescence Microscopy
Published on: January 7, 2019
Combining autocorrelation signals with delay multiply and sum beamforming algorithm for ultrasound imaging
Ke Song1,2, Paul Liu3, Dong C Liu4
1College of Computer Science, Sichuan University, Chengdu, 610065, China. songke_personal@126.com.
Abstract:
Beamformer is one of the most important components in ultrasound imaging system. The delay and sum (DAS) beamforming algorithm has been widely used in recent decades due to its simplicity and robustness. However, it has poor impact on resolution and contrast. A new beamformer named filtered delay multiply and sum (F-DMAS) which was an alternative of delay multiply and sum (DMAS) was proposed to overcome these shortcomings of DAS. Although F-DMAS partially enhances the image quality, its performance still has room for improvement. Therefore, a novel beamformer named lag-based delay multiply and sum (L-DMAS) which combines autocorrelation signals with DMAS algorithm is proposed by us to improve its efficiency. Field II was employed to synthesize a point target phantom and a cyst phantom to compare the performance between DAS, F-DMAS, double stage delay multiply and sum (DS-DMAS), and L-DMAS. We also estimate the performance of four algorithms on experimental data and in vivo data. These results show that both DS-DMAS and L-DMAS are better than DAS and F-DMAS in each case. In some cases, DS-DMAS and L-DMAS have little difference in performance, but in other cases, L-DMAS outperforms DS-DMAS. Graphical Abstract.
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