Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Mode Visualization and Control of Complex Lasers Using Neural Networks.

ACS photonics·2025

Same author

Tailoring hydrogen storage performance of Mg-Mg<sub>2</sub>Ni alloys: synergistic effects of composition and phase formation with first-principles insights.

RSC advances·2025

Same author

Roadmap for animate matter.

Journal of physics. Condensed matter : an Institute of Physics journal·2025

Same author

ZnO nanorods grown on Cu wire mesh provide a high sensitivity non-enzymatic absorbance glucose sensor.

Mikrochimica acta·2024

Same author

High quality factor, monodisperse micron-sized random lasers based on porous PLGA spheres.

Optics letters·2024

Same author

Surface Lattice Resonance Lasers with Epitaxial InP Gain Medium.

ACS photonics·2024

Search research articles

Related Experiment Video

Updated: Jan 3, 2026

A Droplet-Based Microfluidic Approach and Microsphere-PCR Amplification for Single-Stranded DNA Amplicons

A Droplet-Based Microfluidic Approach and Microsphere-PCR Amplification for Single-Stranded DNA Amplicons

Published on: November 14, 2018

Protein-based microsphere biolasers fabricated by dehydration.

Toan Van Nguyen¹, Nhat Van Pham, Hanh Hong Mai

¹Department of Physics, Le Quy Don Technical University, Hanoi 100000, Vietnam.

|November 20, 2019

Summary

This summary is machine-generated.

Researchers developed a fast, green method to create biocompatible microsphere biolasers from bovine serum albumin (BSA). These solid-state biolasers show potential for biosensing applications.

More Related Videos

Image-guided, Laser-based Fabrication of Vascular-derived Microfluidic Networks

Image-guided, Laser-based Fabrication of Vascular-derived Microfluidic Networks

Published on: January 3, 2017

Fabrication of Polymer Microspheres for Optical Resonator and Laser Applications

Fabrication of Polymer Microspheres for Optical Resonator and Laser Applications

Published on: June 2, 2017

Related Experiment Videos

Last Updated: Jan 3, 2026

A Droplet-Based Microfluidic Approach and Microsphere-PCR Amplification for Single-Stranded DNA Amplicons

A Droplet-Based Microfluidic Approach and Microsphere-PCR Amplification for Single-Stranded DNA Amplicons

Published on: November 14, 2018

Image-guided, Laser-based Fabrication of Vascular-derived Microfluidic Networks

Image-guided, Laser-based Fabrication of Vascular-derived Microfluidic Networks

Published on: January 3, 2017

Fabrication of Polymer Microspheres for Optical Resonator and Laser Applications

Fabrication of Polymer Microspheres for Optical Resonator and Laser Applications

Published on: June 2, 2017

Area of Science:

Biophotonics
Materials Science
Biotechnology

Background:

Biolasers offer biocompatibility and biodegradability for biosensing.
Current fabrication methods are complex, slow, and environmentally unfriendly.

Purpose of the Study:

To develop a novel, green, and efficient method for fabricating solid-state microsphere biolasers.
To characterize the properties and potential applications of these novel biolasers.

Main Methods:

Utilized a modified Microglassification™ technology for rapid dehydration of dye-doped bovine serum albumin (BSA) droplets.
Controlled microsphere size (10-150 μm) by adjusting BSA concentration and droplet diameter.
Investigated lasing characteristics under optical pulse excitation.

Main Results:

Successfully fabricated solid-state microsphere biolasers in under 10 minutes.
Achieved a low lasing threshold (7.8 μJ mm-2) and high quality (Q) factor (1700-3100).
Observed size-dependent lasing characteristics consistent with whispering gallery mode (WGM) theory.

Conclusions:

Demonstrated an effective green fabrication technique for high-Q factor microlasers.
These BSA-based microsphere biolasers show promise for advanced biological and chemical sensing.
The developed method offers a scalable and environmentally conscious approach to biolasers.