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Updated: Jan 3, 2026
Dynamic Adhesion Assay for the Functional Analysis of Anti-adhesion Therapies in Inflammatory Bowel Disease
Published on: September 20, 2018
Randomized clinical trial of four adhesion strategies: A 42 month study
Maristela Dutra-Correa1, Vanessa Harumi Kiyan1, Marcia Tonetti Ciaramicoli1
1Department of Operative Dentistry, Postgraduate Program in Dentistry, Paulista University, São Paulo, SP, Brazil.
Context:
The adhesives clinical effectiveness has been extensively reported for noncarious cervical lesions (NCCLs). However, there is a lack of information about the adhesive systems strategies and their effect on NCCL restoration longevity.
Aims:
This study aims to evaluate a 42-month performance of four dentin adhesive systems used for the restorative treatment of NCCLs.
Settings And Design:
NCCLs were randomly divided into four groups: (1) Scotchbond multi-purpose (MP); 2: Single bond plus (SB); 3: Scotchbond SE (SE); and 4: Easy bond (EB).
Subjects And Methods:
NCCLs (125) were randomly distributed: (1) MP; (2) SB; (3) SE; and (4) EB and were restored with a nanofilled resin-composite, evaluated along 18-36-42 months.
Statistical Analysis Used:
Kruskal-Wallis test: Comparison among the adhesive systems in each period. Friedman analysis: Comparison along the periods. Kaplan-Meier: Survival analysis.
Results:
Baseline and 42-month retention (RET) rates (%) were 100/100 for MP; 100/94.74 for SB; 100/87.5 for SE; and 100/100 for EB. The cumulative failure percentage was 9.52% for MP, 9.52% SB, 15.8% SE, and 10% EB. Restorations survival was not dependent on the used adhesive type. Marginal adaptation (MA) was similar to each group, but EB presented noticeable marginal deterioration. Wear was noticed in the 3-step etch-and-rinse (MP) restorations evaluated after 42 months. For the EB, baseline and 18-month wear evaluation were statistically similar. After 36 and 42 months, wear was also similar for EB.
Conclusions:
Adhesive systems showed similar performance within most important adhesive bonding efficiency achievement parameters: RET, MA, interfacial staining, recurrent caries, and postoperative sensitivity evaluated during 42 months.
