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Remediating reduced memory specificity in bipolar disorder: A case study using a Computerized Memory Specificity

Kris Martens1, Keisuke Takano2, Tom J Barry3,4

  • 1Faculty of Psychology and Educational Sciences, KU Leuven, Leuven, Belgium.

Brain and Behavior
|November 21, 2019
PubMed
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This summary is machine-generated.

Computerized Memory Specificity Training (c-MeST) improved autobiographical memory specificity in a patient with bipolar disorder. However, other symptoms did not improve and temporarily worsened during training.

Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Neuroscience

Background:

  • Reduced autobiographical memory specificity (rAMS) is a vulnerability factor in various mental health conditions, including bipolar disorder (BD).
  • Memory Specificity Training (MeST) has shown efficacy in remediating rAMS in other disorders like unipolar depression and PTSD.
  • The impact of MeST on BD has not been previously investigated.

Purpose of the Study:

  • To examine the effectiveness of a computerized version of Memory Specificity Training (c-MeST) in improving autobiographical memory specificity (AMS) in an individual with rapid cycling type I BD.
  • To assess the downstream effects of c-MeST on related psychological processes and symptoms in the participant.

Main Methods:

  • An experimental case study employing an ABA single-subject design.
Keywords:
Memory Specificity Trainingautobiographical memorybipolar disorderreduced autobiographical memory specificity

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  • Repeated measures of memory specificity, depressive symptoms, and related psychological processes and symptoms were taken during baseline, training, and follow-up phases.
  • The intervention involved nine sessions of computerized Memory Specificity Training (c-MeST) over 17 days.

    • Main Results:

    • Significant improvement in memory specificity (AMS) was observed following the completion of c-MeST.
    • AMS showed the most substantial improvement from the initial in-person assessment to the first online training session.
    • Other psychological processes and symptoms initially deteriorated during the training phase but returned to baseline levels during the 1-month follow-up.

    Conclusions:

    • Computerized Memory Specificity Training (c-MeST) effectively enhanced autobiographical memory specificity in a patient with rapid cycling BD.
    • No significant improvements in other depressive symptoms or related psychological processes were observed.
    • Some maladaptive psychological processes and symptoms worsened during training but resolved by follow-up, indicating a need for further research.