Related Experiment Video
Updated: Jan 3, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Benzodiazepines use in Morocco: A nation wide consumption database study between 2004 and 2017
Zidane Qriouet1, Abdelmajid Belaiche2, Zineb Qmichou3
1Centre de biotechnologie médicale, Moroccan foundation for Science, Innovation & Research (MAScIR), Rabat, Morocco; Laboratoire de Pharmacologie et Toxicologie, Faculté de Médecine et de pharmacie, Université Mohammed V-Souissi, Rabat, Morocco.
This study reveals benzodiazepine (BZD) consumption trends in Morocco from 2004-2017. Bromazepam was most used until 2016, with Alprazolam leading in 2017, highlighting evolving BZD prescription patterns.
Area of Science:
- Pharmacology
- Public Health
- Drug Utilization Studies
Background:
- Limited data exists on benzodiazepine (BZD) consumption rates in Morocco.
- Understanding prescription patterns is crucial for public health initiatives and drug safety.
Purpose of the Study:
- To describe the prescription rate and consumption trends of benzodiazepines and their agonists in Morocco.
- To provide baseline data for analytical toxicology and health organizations.
Main Methods:
- Retrospective descriptive analysis of BZD and agonist sales data.
- Utilized the IQVIA database for the period 2004-2017.
- Data expressed as daily defined doses per 1000 inhabitants per day (DDD/1000 inh/day).
Main Results:
- Bromazepam was the most consumed BZD from 2004-2016.
- In 2017, Alprazolam became the most consumed, followed by Bromazepam.
- Total annual consumption of BZDs and agonists showed an increasing trend from 2004 to 2014, then a slight decrease.
Conclusions:
- This is the first study detailing BZD and agonist consumption in Morocco.
- Findings provide essential data for developing targeted BZD detection and quantification methods for the Moroccan population.
- Highlights the need for continued monitoring of psychotropic drug utilization.
Related Concept Videos
Sedatives and Hypnotics Drugs: Benzodiazepines
Benzodiazepines work by enhancing the effects of the inhibitory neurotransmitter GABA. They bind to the GABAA receptor, increasing its affinity for GABA, which opens chloride...
Anxiolytic Drugs: Benzodiazepines and Buspirone
CNS Depressants: Barbiturates and Benzodiazepines
Sedatives and Hypnotics Drugs: Miscellaneous Agents
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
Pharmacodynamics in Geriatric Patients: Effects of Age
Sedatives and Hypnotics: Overview
Sedative-hypnotics are categorized into barbiturates, benzodiazepines (BZDs), and non-benzodiazepines or Z-drugs. These drugs work by suppressing central nervous system activity, and this suppression is dose-dependent. Older sedative medications, like barbiturates, follow a linear curve in...

