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Updated: Jul 31, 2026
High-throughput Assay to Phenotype Salmonella enterica Typhimurium Association, Invasion, and Replication in Macrophages
Published on: August 11, 2014
Interaction of Salmonella enteritidis and Salmonella typhimurium in Microbial Association Formed by Them in In Vitro
A V Rakov1, A A Yakovlev2, N A Kuznetsova2
1G. P. Somov Research Institute of Epidemiology and Microbiology, Vladivostok, Russia. alexeyrakov@mail.ru.
Abstract:
We studied the interaction of Salmonella enteritidis and Salmonella typhimurium in the microbial association formed by these microorganisms in vitro. It was found that S. typhimurium in microbial association in LB-broth inhibited reproduction of S. enteritidis, which attested to its higher competitiveness. The concentration of S. typhimurium in the medium in 6 h reached 92-93% of the total number of bacteria. Parallel growth of the populations of S. enteritidis and S. typhimurium was observed only during the first hour, but later, S. typhimurium always exceeded S. enteritidis by the growth dynamics. The competitive advantage of S. typhimurium was observed both in the absence and presence of 60-MDa virulence plasmid.
