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Updated: Jan 3, 2026

Heterogeneous Removal of Water-Soluble Ruthenium Olefin Metathesis Catalyst from Aqueous Media Via Host-Guest Interaction
Published on: August 23, 2018
Ruthenium-Catalyzed Selective Hydrogenation of Epoxides to Secondary Alcohols
Subramanian Thiyagarajan1, Chidambaram Gunanathan1
1School of Chemical Sciences , National Institute of Science Education and Research, HBNI , Bhubaneswar 752050 , India.
Abstract:
A ruthenium(II)-catalyzed highly selective Markovnikov hydrogenation of terminal epoxides to secondary alcohols is reported. Diverse substitutions on the aryl ring of styrene oxides are tolerated. Benzylic, glycidyl, and aliphatic epoxides as well as diepoxides also underwent facile hydrogenation to provide secondary alcohols with exclusive selectivity. Metal-ligand cooperation-mediated ruthenium trans-dihydride formation and its reaction involving oxygen and the less substituted terminal carbon of the epoxide is envisaged for the origin of the observed selectivity.
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