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Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

668
Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
668
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

139
Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
139
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

243
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
243
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

251
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
251
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

274
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
274
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

286
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
286

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Related Experiment Video

Updated: Jan 2, 2026

Author Spotlight: A Neonatal Heterotopic Rat Heart Transplantation Model for the Study of Endothelial-to-Mesenchymal Transition
08:38

Author Spotlight: A Neonatal Heterotopic Rat Heart Transplantation Model for the Study of Endothelial-to-Mesenchymal Transition

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Renal Replacement Therapy in Neonates.

Benjamin L Spector1, Jason M Misurac2

  • 1Department of Pediatrics.

Neoreviews
|December 4, 2019
PubMed
Summary

Acute kidney injury (AKI) affects many neonates in the NICU. This review details renal replacement therapy (RRT) options like peritoneal dialysis, hemodialysis, and continuous RRT for critical infant care.

Area of Science:

  • Neonatal Medicine
  • Nephrology
  • Critical Care

Background:

  • Acute kidney injury (AKI) is a significant concern in neonatal intensive care units (NICUs), impacting up to 25% of critically ill infants.
  • While medical management is primary, renal replacement therapy (RRT) becomes necessary when conservative treatments fail to manage fluid balance, electrolytes, or toxin levels.

Purpose of the Study:

  • To provide a comprehensive overview of RRT modalities used in neonatal populations.
  • To discuss the technical aspects, benefits, indications, contraindications, and potential complications of each RRT method.

Main Methods:

  • This is a review article.
  • It synthesizes information on peritoneal dialysis, hemodialysis, and continuous RRT.

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Main Results:

  • The review introduces various RRT modalities available for neonates.
  • It details the specific considerations for each type of RRT.

Conclusions:

  • Understanding different RRT modalities is crucial for managing AKI in neonates.
  • This review serves as a guide for clinicians regarding the application and management of RRT in critically ill infants.