Related Experiment Video
Updated: Jan 2, 2026

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
Published on: August 9, 2012
Evaluation and Long-term Management of Neurogenic Bladder in Spinal Dysraphism
Hoang-Kim Le1, Diana Cardona-Grau2, George Chiang1
1Division of Pediatric Urology, Rady Children's Hospital San Diego, University of California San Diego, San Diego, CA.
Abstract:
Spinal dysraphism, which includes conditions such as myelomeningocele and sacral agenesis, is one of the most common causes of congenital lower urinary tract dysfunction. Early evaluation of the neurogenic bladder serves to minimize renal damage, and the main goals of management include preserving renal function, achieving acceptable continence, and optimizing quality of life. The survival of patients with such conditions has improved to greater than 80% reaching adulthood, owing to advances in diagnostic and therapeutic modalities. The result is a real, and unfortunately often unmet, need for successful transitional care in this complex patient population. Clinicians must be able to identify the unique challenges encountered by patients with neurogenic bladder as they shift through different stages of their life.
Related Concept Videos
Urinary Tract Infection IV: Nursing Management
The Micturition Reflex
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
Urinary Tract Calculi V: Nursing Management
Imaging Studies VI: Voiding Cystourethrography and Cystography
Nursing Assessment of the Genitourinary System I: Health History
Anatomy of the Genitourinary System II: Bladder and Urethra

