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Nail manifestations in atopic dermatitis: a systematic review
Wei Qiang Chng1, Yik Weng Yew2
1Department of Internal Medicine, National University Hospital, Singapore, Singapore.
International Journal of Dermatology
|December 4, 2019
Summary
Nail changes are common in atopic dermatitis (AD), affecting patients of all ages. This systematic review quantifies the prevalence of these nail disorders in AD patients, aiding early diagnosis and management.
Area of Science:
- Dermatology
- Clinical Research
- Systematic Review
Background:
- Nail involvement in atopic dermatitis (AD) is understudied.
- A wide spectrum of nail disorders is associated with AD.
- Previous studies lack a comprehensive overview of nail manifestation prevalence in AD.
Purpose of the Study:
- To systematically review and quantify the prevalence of nail disorders in patients with atopic dermatitis.
- To identify nail changes as potential early diagnostic clues for AD.
- To understand the spectrum of nail complications in AD.
Main Methods:
- Systematic review of English and non-English articles from MEDLINE, EMBASE, and Cochrane databases.
- Inclusion of studies reporting nail changes specifically in atopic dermatitis patients.
- Descriptive summarization of extracted data from 12 studies, encompassing 13 cohorts.
Main Results:
- Twelve studies reported the proportion of nail changes in atopic dermatitis patients.
- Data from 13 distinct cohorts were analyzed.
- The review synthesized existing evidence on AD-associated nail manifestations.
Conclusions:
- Increased awareness of nail changes in AD is crucial for physicians.
- Understanding the prevalence and types of nail disorders can improve AD patient care.
- Nail manifestations may serve as indicators for AD diagnosis and management.
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