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Updated: Jan 2, 2026

An Integrated Workflow of Identification and Quantification on FDR Control-Based Untargeted Metabolome
Published on: September 20, 2022
Reactome and ORCID-fine-grained credit attribution for community curation.
Guilherme Viteri1, Lisa Matthews2, Thawfeek Varusai1
1European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
Reactome enhances biomolecular pathway knowledge base accessibility by making contributor names searchable and enabling ORCID integration. This boosts visibility and engagement for authors, curators, and reviewers.
Area of Science:
- Biochemistry
- Bioinformatics
- Molecular Biology
Background:
- Reactome is a manually curated, open-source knowledge base of biomolecular pathways.
- It has historically provided credit attribution for authors, curators, and reviewers at reaction and pathway levels.
- Attribution data are accessible via the web interface and data downloads.
Purpose of the Study:
- To improve visibility and credit attribution for Reactome contributors.
- To foster greater community engagement with the Reactome knowledge base.
- To enhance the accuracy and comprehensiveness of pathway data.
Main Methods:
- Implemented full searchability of contributor names within the Reactome web interface.
- Enabled contributors to claim their contributions directly to their ORCID profiles.
- Introduced a 'Contribution' section to solicit expert review and editing of pathways.
Main Results:
- Contributor names are now fully searchable, increasing discoverability.
- Contributors can easily link their Reactome work to their ORCID profiles.
- A new community review process has been initiated for pathway data.
Conclusions:
- These changes enhance recognition for Reactome contributors.
- The updates facilitate deeper community involvement in pathway curation.
- Reactome is better positioned to maintain a high-quality, community-driven resource.
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