[NEW METHODS AND PERSPECTIVE APPROACHES TO FOOD ALLERGY THERAPY IN CHILDREN]

The purpose is to analyze literature data on currently used and promising approaches to the treatment of food allergies in children. It reviewed the variants of allergen-specific food allergy therapy (AST-FA), which allow expanding the range of consumed products to which no reaction is manifested, reducing the risk of developing potential life-threatening allergic reactions if they are accidentally ingested. AST-FA is currently the only potentially effective method of IgE-mediated FA. One of the new options for pathogenetically substantiated therapy of FA is the use of biological drugs that increase the ability to achieve immune tolerance to food antigens. It seems reasonable to consider the possibilities of using a number of non-allergen-specific molecules - cytokines, Toll-like receptors, various cell populations, probiotics and gene therapy - as potential targets for treating patients with multiple food allergies. Further studies are needed to determine the optimal dose, duration of treatment, and long-term effects of biologics used in the treatment of FA.