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Published on: June 10, 2021
Fluorinated maleimide-substituted porphyrins and chlorins: synthesis and characterization
Valentina A Ol'shevskaya1, Elena G Kononova1, Andrei V Zaitsev1
1A. N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, 119991, Vavilova St. 28, Moscow, Russian Federation.
Abstract:
Maleimide-containing fluorinated porphyrins and chlorins were prepared based on the reaction of Zn(II) or Ni(II) complexes of 5,10,15,20-tetrakis(4-amino-2,3,5,6-tetrafluorophenyl)porphyrin and chlorin with maleic anhydride. Porphyrin maleimide derivatives were also prepared by the reaction of 5,10,15,20-tetrakis(4-azido-2,3,5,6-tetrafluorophenyl)porphyrinato Zn(II) or Ni(II) with N-propargylmaleimide via the CuAAC click reaction to afford fluorinated porphyrin-triazole-maleimide conjugates. New maleimide derivatives were isolated in reasonable yields and identified by UV-vis, 1H NMR, 19F NMR spectroscopy and mass-spectrometry.
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