Program evaluation of the Opioid and Naloxone Education (ONE Rx) program using the RE-AIM model

Area of Science:

• Public Health
• Pharmacology
• Health Services Research

Background:

• Opioid misuse and accidental overdose pose significant public health challenges.
• Community pharmacy-based interventions are crucial for mitigating opioid-related harms.
• The Opioid and Naloxone Education (ONE Rx) program was developed to address these issues through patient screening and pharmacist interventions.

Purpose of the Study:

• To describe the implementation of the ONE Rx program.
• To report on the population-level impact of ONE Rx using the RE-AIM Model.
• To discuss future implications and areas for improvement of the program.

Main Methods:

• The study evaluated the ONE Rx program using the five domains of the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) Model.
• Reach was measured by patient screening completion proportion.
• Effectiveness was defined by pharmacist intervention rates for at-risk patients. Adoption, Implementation, and Maintenance were assessed through pharmacy enrollment and sustained screening rates.

Main Results:

• Approximately 16.9% of patients receiving opioid prescriptions were screened.
• A high proportion (97.1%) of screened patients identified as at-risk received pharmacist interventions.
• Pharmacy adoption and maintenance rates were 44.8% and 80.0% respectively, indicating program sustainability.

Conclusions:

• The ONE Rx program demonstrated significant success and positive population impact, particularly in efficacy, adoption, and maintenance.
• Areas identified for improvement include increasing patient reach and enhancing implementation strategies.
• The findings highlight the potential of community pharmacy-based programs in addressing the opioid crisis.