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Published on: October 10, 2019
Tracking Changes in Clinical Practice Patterns Following Prebiopsy Biparametric Prostate MRI
Moon Hyung Choi1, Young Joon Lee1, Seung Eun Jung1
1Department of Radiology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 1021 Tongil-ro, Eunpyeong-gu, Seoul 03312, Republic of Korea; Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea; Catholic Smart Imaging Center, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Prebiopsy biparametric MRI significantly changed clinical practice for suspected prostate cancer, increasing MRI use and biopsy avoidance. This imaging is valuable for identifying clinically significant prostate cancer.
Area of Science:
- Urology
- Radiology
- Oncology
Background:
- Prostate cancer diagnosis relies on biopsy, which can be invasive.
- Prebiopsy MRI aims to improve diagnostic accuracy and patient selection for biopsy.
Purpose of the Study:
- To assess changes in clinical practice following the introduction of prebiopsy biparametric MRI.
- To evaluate the benefits of prebiopsy MRI in a real-world clinical setting.
Main Methods:
- Retrospective analysis of 1,661 patients undergoing biopsy for suspected prostate cancer (Oct 2015 - Mar 2018).
- Study divided into five 6-month periods to track temporal practice changes after MRI implementation (Apr 2016).
- Comparison of biopsy outcomes based on MRI status (no MRI, negative MRI, positive MRI).
Main Results:
- Proportion of patients undergoing prebiopsy MRI increased from 22.6% to 84.4% (P < 0.001).
- Biopsy avoidance based on MRI results rose from 9.0% to 48.1% (P < 0.001).
- Lower cancer detection rates and positive cores observed in the negative MRI group.
Conclusions:
- Biparametric MRI has been successfully integrated into clinical practice for prostate cancer diagnosis.
- Prebiopsy MRI is effective in stratifying the risk of clinically significant prostate cancer.
