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Cardiovascular Disease Risk in Survivors of Breast Cancer
Avinash V Sharma1, Gemma Reddin2, Brian Forrestal1,2
1MedStar Washington Hospital Center, Washington, DC, USA.
Current Treatment Options in Cardiovascular Medicine
|December 11, 2019
Summary
Breast cancer survivors face increased cardiovascular disease risk due to treatments like anthracyclines and radiation. Optimal long-term heart health management for these patients requires further research and clear guidelines.
Area of Science:
- Cardiology
- Oncology
- Cancer Survivorship
Background:
- Improved breast cancer treatments lead to more survivors.
- Cardiovascular disease (CVD) is a major cause of morbidity and mortality in breast cancer survivors.
- Knowledge gaps exist regarding optimal long-term CVD management in this population.
Purpose of the Study:
- To review current evidence on cardiovascular effects of breast cancer therapies.
- To provide recommendations for diagnosing and managing CVD in breast cancer patients and survivors.
- To highlight ongoing research initiatives informing clinical care.
Main Methods:
- Literature review of recent evidence on cardiovascular effects of breast cancer treatments.
- Synthesis of recommendations for diagnosis and management across the cancer treatment continuum.
- Discussion of current research and its clinical implications.
Main Results:
- Breast cancer and CVD share common risk factors.
- Cancer therapies (anthracyclines, radiation, hormonal therapy) can exacerbate or induce CVD.
- Evidence supports integrated management strategies from treatment through survivorship.
Conclusions:
- Cardiovascular health is critical for breast cancer survivors.
- Multidisciplinary management is essential to mitigate treatment-related CVD.
- Further research is needed to optimize long-term cardiovascular care for cancer survivors.
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