Stem cells and oral surgery: A systematic review.

Area of Science:

• Oral and Maxillofacial Surgery
• Regenerative Medicine
• Dental Implantology

Background:

• Structural defects in oral surgery arise from cystic/tumoral pathology, periodontitis, and maxillary atrophy.
• Dental implant rehabilitation is often necessitated by maxillary atrophy.
• Stem cells present a novel regenerative approach for oral cavity defects.

Purpose of the Study:

• To systematically review stem cell applications in oral surgery.
• To evaluate the potential of stem cells in future oral treatments.
• To bridge basic research findings with clinical applications.

Main Methods:

• Systematic literature review of stem cell research in oral surgery since 2000.
• Adherence to PRISMA statement guidelines.
• Utilized PRISMA flow chart for study selection.

Main Results:

• Clinical conclusions drawn from basic and early clinical research.
• Focus on accelerating the application of regenerative therapies.
• Identification of potential for excellence in regenerative treatments.

Conclusions:

• Stem cells represent a potential turning point in tissue regeneration.
• Significant obstacles remain for stem cells to become a standard therapeutic alternative.
• Key areas include stem cells, oral surgery, cell therapy, and regeneration.