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Updated: Jan 1, 2026
A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
[A new guaiane-type sesquiterpenoid from Croton yunnanensis]
Hui-Mei You1, Juan-Rong Zhang1, Zhi-Heng Zhao1
1State Key Laboratory of Education Ministry-State Minority Committee of National Medicine Resource Chemistry,School of Ethnic Medicine,Yunnan Minzu University Kunming 650500,China.
Abstract:
Five sesquiterpenoids were isolated from 90% ethanol extract of Croton yunnanensis by silica gel,Sephadex LH-20 column chromatography,as well as prep-HPLC methods. Based on MS,1 D and 2 D NMR spectral analyses,the structures of the five compounds were identified as 11-methoxyl alismol(1),6β,7β-epoxy-4α-hydroxyguaian-10-ene(orientalol C,2),multisalactone D(3),arvestonol(4),and 4,5-dihydroblumenol A(5). Compound 1 was a new guaiane-type sesquiterpenoid. Compounds 2-4 were isolated from the Croton genus for the first time,and compound 5 was obtained from this plant for the first time.
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